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Statins as Potential Chemoprevention or Therapeutic Agents in Cancer: a Model for Evaluating Repurposed Drugs.
Published in:
Current Oncology Reports, 2021, v. 23, n. 3, p. 1, doi. 10.1007/s11912-021-01023-z
By:
- Joharatnam-Hogan, Nalinie;
- Alexandre, Leo;
- Yarmolinsky, James;
- Lake, Blossom;
- Capps, Nigel;
- Martin, Richard M;
- Ring, Alistair;
- Cafferty, Fay;
- Langley, Ruth E
Publication type:
Article
Effect of tea on blood pressure for secondary prevention of cardiovascular disease: a systematic review and meta-analysis of randomized controlled trials.
Published in:
Nutrition Reviews, 2015, v. 73, n. 4, p. 236, doi. 10.1093/nutrit/nuv001
By:
- Yarmolinsky, James;
- Gon, Giorgia;
- Edwards, Phil
Publication type:
Article
Genetically proxied glucose-lowering drug target perturbation and risk of cancer: a Mendelian randomisation analysis.
Published in:
Diabetologia, 2023, v. 66, n. 8, p. 1481, doi. 10.1007/s00125-023-05925-4
By:
- Yarmolinsky, James;
- Bouras, Emmanouil;
- Constantinescu, Andrei;
- Burrows, Kimberley;
- Bull, Caroline J.;
- Vincent, Emma E.;
- Martin, Richard M.;
- Dimopoulou, Olympia;
- Lewis, Sarah J.;
- Moreno, Victor;
- Vujkovic, Marijana;
- Chang, Kyong-Mi;
- Voight, Benjamin F.;
- Tsao, Philip S.;
- Gunter, Marc J.;
- Hampe, Jochen;
- Pellatt, Andrew J.;
- Pharoah, Paul D. P.;
- Schoen, Robert E.;
- Gallinger, Steven
Publication type:
Article
Sex-specific associations of low birth weight with adult-onset diabetes and measures of glucose homeostasis: Brazilian Longitudinal Study of Adult Health.
Published in:
Scientific Reports, 2016, p. 37032, doi. 10.1038/srep37032
By:
- Yarmolinsky, James;
- Mueller, Noel T;
- Duncan, Bruce B;
- Chor, Dóra;
- Bensenor, Isabela M;
- Griep, Rosane H;
- Appel, Lawrence J;
- Barreto, Sandhi M;
- Schmidt, Maria Inês
Publication type:
Article
Plasminogen activator inhibitor-1 and type 2 diabetes: a systematic review and meta-analysis of observational studies.
Published in:
Scientific Reports, 2016, p. 17714, doi. 10.1038/srep17714
By:
- Yarmolinsky, James;
- Bordin Barbieri, Natália;
- Weinmann, Tobias;
- Ziegelmann, Patricia K.;
- Duncan, Bruce B.;
- Inês Schmidt, Maria
Publication type:
Article
Coffee Consumption, Newly Diagnosed Diabetes, and Other Alterations in Glucose Homeostasis: A Cross-Sectional Analysis of the Longitudinal Study of Adult Health (ELSA-Brasil).
Published in:
PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0126469
By:
- Yarmolinsky, James;
- Mueller, Noel T.;
- Duncan, Bruce B.;
- Bisi Molina, Maria del Carmen;
- Goulart, Alessandra C.;
- Schmidt, Maria Inês
Publication type:
Article
Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study.
Published in:
PLoS Genetics, 2021, v. 17, n. 4, p. 1, doi. 10.1371/journal.pgen.1009525
By:
- Gormley, Mark;
- Yarmolinsky, James;
- Dudding, Tom;
- Burrows, Kimberley;
- Martin, Richard M.;
- Thomas, Steven;
- Tyrrell, Jessica;
- Brennan, Paul;
- Pring, Miranda;
- Boccia, Stefania;
- Olshan, Andrew F.;
- Diergaarde, Brenda;
- Hung, Rayjean J.;
- Liu, Geoffrey;
- Legge, Danny;
- Tajara, Eloiza H.;
- Severino, Patricia;
- Lacko, Martin;
- Ness, Andrew R.;
- Davey Smith, George
Publication type:
Article
Applying Mendelian randomization to appraise causality in relationships between nutrition and cancer.
Published in:
Cancer Causes & Control, 2022, v. 33, n. 5, p. 631, doi. 10.1007/s10552-022-01562-1
By:
- Wade, Kaitlin H.;
- Yarmolinsky, James;
- Giovannucci, Edward;
- Lewis, Sarah J.;
- Millwood, Iona Y.;
- Munafò, Marcus R.;
- Meddens, Fleur;
- Burrows, Kimberley;
- Bell, Joshua A.;
- Davies, Neil M.;
- Mariosa, Daniela;
- Kanerva, Noora;
- Vincent, Emma E.;
- Smith-Byrne, Karl;
- Guida, Florence;
- Gunter, Marc J.;
- Sanderson, Eleanor;
- Dudbridge, Frank;
- Burgess, Stephen;
- Cornelis, Marilyn C.
Publication type:
Article
Mendelian randomization does not support serum calcium in prostate cancer risk.
Published in:
2018
By:
- Yarmolinsky, James;
- Berryman, Katie;
- Langdon, Ryan;
- Bonilla, Carolina;
- PRACTICAL consortium;
- Davey Smith, George;
- Martin, Richard M.;
- Lewis, Sarah J.
Publication type:
journal article
Identifying molecular mediators of the relationship between body mass index and endometrial cancer risk: a Mendelian randomization analysis.
Published in:
2022
By:
- Hazelwood, Emma;
- Sanderson, Eleanor;
- Tan, Vanessa Y.;
- Ruth, Katherine S.;
- Frayling, Timothy M.;
- Dimou, Niki;
- Gunter, Marc J.;
- Dossus, Laure;
- Newton, Claire;
- Ryan, Neil;
- Pournaras, Dimitri J.;
- O'Mara, Tracy A.;
- Davey Smith, George;
- Martin, Richard M.;
- Yarmolinsky, James
Publication type:
journal article
Association of germline TYK2 variation with lung cancer and non‐Hodgkin lymphoma risk.
Published in:
International Journal of Cancer, 2022, v. 151, n. 12, p. 2155, doi. 10.1002/ijc.34180
By:
- Yarmolinsky, James;
- Amos, Christopher I.;
- Hung, Rayjean J.;
- Moreno, Victor;
- Burrows, Kimberley;
- Smith‐Byrne, Karl;
- Atkins, Joshua R.;
- Brennan, Paul;
- McKay, James D.;
- Martin, Richard M.;
- Davey Smith, George
Publication type:
Article
Age at first childbirth and newly diagnosed diabetes among postmenopausal women: a cross-sectional analysis of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).
Published in:
Sao Paulo Medical Journal, 2017, v. 135, n. 3, p. 266, doi. 10.1590/1516-3180.2017.0015240217
By:
- Yarmolinsky, James;
- Bartholow Duncan, Bruce;
- Barreto, Sandhi Maria;
- de Fátima Sander Diniz, Maria;
- Chor, Dora;
- Inês Schmidt, Maria
Publication type:
Article
Association between genetically proxied PCSK9 inhibition and prostate cancer risk: A Mendelian randomisation study.
Published in:
PLoS Medicine, 2023, v. 19, n. 1, p. 1, doi. 10.1371/journal.pmed.1003988
By:
- Fang, Si;
- Yarmolinsky, James;
- Gill, Dipender;
- Bull, Caroline J.;
- Perks, Claire M.;
- Davey Smith, George;
- Gaunt, Tom R.;
- Richardson, Tom G.
Publication type:
Article
Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis.
Published in:
PLoS Medicine, 2022, v. 19, n. 2, p. 1, doi. 10.1371/journal.pmed.1003897
By:
- Yarmolinsky, James;
- Díez-Obrero, Virginia;
- Richardson, Tom G.;
- Pigeyre, Marie;
- Sjaarda, Jennifer;
- Paré, Guillaume;
- Walker, Venexia M.;
- Vincent, Emma E.;
- Tan, Vanessa Y.;
- Obón-Santacana, Mireia;
- Albanes, Demetrius;
- Hampe, Jochen;
- Gsur, Andrea;
- Hampel, Heather;
- Pai, Rish K.;
- Jenkins, Mark;
- Gallinger, Steven;
- Casey, Graham;
- Zheng, Wei;
- Amos, Christopher I.
Publication type:
Article
Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis.
Published in:
2022
By:
- Yarmolinsky, James;
- Díez-Obrero, Virginia;
- Richardson, Tom G;
- Pigeyre, Marie;
- Sjaarda, Jennifer;
- Paré, Guillaume;
- Walker, Venexia M;
- Vincent, Emma E;
- Tan, Vanessa Y;
- Obón-Santacana, Mireia;
- Albanes, Demetrius;
- Hampe, Jochen;
- Gsur, Andrea;
- Hampel, Heather;
- Pai, Rish K;
- Jenkins, Mark;
- Gallinger, Steven;
- Casey, Graham;
- Zheng, Wei;
- Amos, Christopher I
Publication type:
journal article
Genetically proxied IL-1 receptor antagonism and risk of polymyalgia rheumatica.
Published in:
Rheumatology, 2024, v. 63, n. 2, p. e43, doi. 10.1093/rheumatology/kead423
By:
- Zhao, Sizheng Steven;
- Rajeswaran, Thurkka;
- Mackie, Sarah L;
- Yarmolinsky, James
Publication type:
Article
Mendelian Randomization and Bayesian Colocalization Analysis Implicate Glycoprotein VI as a Potential Drug Target for Cardioembolic Stroke in South Asian Populations.
Published in:
Journal of the American Heart Association, 2024, v. 13, n. 16, p. 1, doi. 10.1161/JAHA.124.035008
By:
- Siwei Wu;
- Meena, Devendra;
- Yarmolinsky, James;
- Gill, Dipender;
- Smith, Alexander;
- Dib, Marie-Joe;
- Chauhan, Ganesh;
- Rohatgi, Anand;
- Dehghan, Abbas;
- Tzoulaki, Ioanna
Publication type:
Article
Mendelian randomisation analysis of circulating adipokines and C‐reactive protein on breast cancer risk.
Published in:
International Journal of Cancer, 2020, v. 147, n. 6, p. 1597, doi. 10.1002/ijc.32947
By:
- Robinson, Timothy;
- Martin, Richard M.;
- Yarmolinsky, James
Publication type:
Article
Strengthening the Reporting of Observational Studies in Epidemiology Using Mendelian Randomization: The STROBE-MR Statement.
Published in:
JAMA: Journal of the American Medical Association, 2021, v. 326, n. 16, p. 1614, doi. 10.1001/jama.2021.18236
By:
- Skrivankova, Veronika W.;
- Richmond, Rebecca C.;
- Woolf, Benjamin A. R.;
- Yarmolinsky, James;
- Davies, Neil M.;
- Swanson, Sonja A.;
- VanderWeele, Tyler J.;
- Higgins, Julian P. T.;
- Timpson, Nicholas J.;
- Dimou, Niki;
- Langenberg, Claudia;
- Golub, Robert M.;
- Loder, Elizabeth W.;
- Gallo, Valentina;
- Tybjaerg-Hansen, Anne;
- Davey Smith, George;
- Egger, Matthias;
- Richards, J. Brent
Publication type:
Article
Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer.
Published in:
2020
By:
- Yarmolinsky, James;
- Bull, Caroline J.;
- Vincent, Emma E.;
- Robinson, Jamie;
- Walther, Axel;
- Smith, George Davey;
- Lewis, Sarah J.;
- Relton, Caroline L.;
- Martin, Richard M.
Publication type:
journal article
Appraising the role of previously reported risk factors in epithelial ovarian cancer risk: A Mendelian randomization analysis.
Published in:
2019
By:
- Yarmolinsky, James;
- Relton, Caroline L.;
- Lophatananon, Artitaya;
- Muir, Kenneth;
- Menon, Usha;
- Gentry-Maharaj, Aleksandra;
- Walther, Axel;
- Zheng, Jie;
- Fasching, Peter;
- Zheng, Wei;
- Yin Ling, Woo;
- Park, Sue K.;
- Kim, Byoung-Gie;
- Choi, Ji-Yeob;
- Park, Boyoung;
- Davey Smith, George;
- Martin, Richard M.;
- Lewis, Sarah J.
Publication type:
journal article
Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis.
Published in:
2022
By:
- Bouras, Emmanouil;
- Karhunen, Ville;
- Gill, Dipender;
- Huang, Jian;
- Haycock, Philip C;
- Gunter, Marc J;
- Johansson, Mattias;
- Brennan, Paul;
- Key, Tim;
- Lewis, Sarah J;
- Martin, Richard M;
- Murphy, Neil;
- Platz, Elizabeth A;
- Travis, Ruth;
- Yarmolinsky, James;
- Zuber, Verena;
- Martin, Paul;
- Katsoulis, Michail;
- Freisling, Heinz;
- Nøst, Therese Haugdahl
Publication type:
journal article
Identification of potential mediators of the relationship between body mass index and colorectal cancer: a Mendelian randomization analysis.
Published in:
International Journal of Epidemiology, 2024, v. 53, n. 3, p. 1, doi. 10.1093/ije/dyae067
By:
- Bouras, Emmanouil;
- Gill, Dipender;
- Zuber, Verena;
- Murphy, Neil;
- Dimou, Niki;
- Aleksandrova, Krasimira;
- Lewis, Sarah J;
- Martin, Richard M;
- Yarmolinsky, James;
- Albanes, Demetrius;
- Brenner, Hermann;
- Castellví-Bel, Sergi;
- Chan, Andrew T;
- Cheng, Iona;
- Gruber, Stephen;
- Guelpen, Bethany Van;
- Li, Christopher I;
- Marchand, Loic Le;
- Newcomb, Polly A;
- Ogino, Shuji
Publication type:
Article
Investigating the transparency of reporting in two-sample summary data Mendelian randomization studies using the MR-Base platform.
Published in:
International Journal of Epidemiology, 2022, v. 51, n. 6, p. 1943, doi. 10.1093/ije/dyac074
By:
- Woolf, Benjamin;
- Cara, Nina Di;
- Moreno-Stokoe, Christopher;
- Skrivankova, Veronika;
- Drax, Katie;
- Higgins, Julian P T;
- Hemani, Gibran;
- Munafò, Marcus R;
- Smith, George Davey;
- Yarmolinsky, James;
- Richmond, Rebecca C
Publication type:
Article
Mendelian randomization applied to pharmaceutical use: the case of metformin and lung cancer.
Published in:
2020
By:
- Yarmolinsky, James;
- Bull, Caroline J;
- Walker, Venexia M;
- Nounu, Aayah;
- Smith, George Davey;
- Davey Smith, George
Publication type:
Letter
Letter regarding article, "Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis".
Published in:
2019
By:
- Tan, Vanessa Y;
- Yarmolinsky, James;
- Lawlor, Debbie A;
- Timpson, Nicholas J
Publication type:
Letter
Commentary: Mendelian randomization analysis identifies circulating vitamin D as a causal risk factor for ovarian cancer.
Published in:
2016
By:
- Bull, Caroline J.;
- Yarmolinsky, James;
- Wade, Kaitlin H.
Publication type:
journal article
Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46834-3
By:
- Smith-Byrne, Karl;
- Hedman, Åsa;
- Dimitriou, Marios;
- Desai, Trishna;
- Sokolov, Alexandr V.;
- Schioth, Helgi B.;
- Koprulu, Mine;
- Pietzner, Maik;
- Langenberg, Claudia;
- Atkins, Joshua;
- Penha, Ricardo Cortez;
- McKay, James;
- Brennan, Paul;
- Sirui Zhou;
- Richards, Brent J.;
- Yarmolinsky, James;
- Martin, Richard M.;
- Borlido, Joana;
- Mu, Xinmeng J.;
- Butterworth, Adam
Publication type:
Article
Strategies to investigate and mitigate collider bias in genetic and Mendelian randomisation studies of disease progression.
Published in:
PLoS Genetics, 2023, v. 18, n. 2, p. 1, doi. 10.1371/journal.pgen.1010596
By:
- Mitchell, Ruth E.;
- Hartley, April E.;
- Walker, Venexia M.;
- Gkatzionis, Apostolos;
- Yarmolinsky, James;
- Bell, Joshua A.;
- Chong, Amanda H. W.;
- Paternoster, Lavinia;
- Tilling, Kate;
- Smith, George Davey
Publication type:
Article
Variation in Urban and Rural Water Fluoride Levels in Ontario.
Published in:
Journal of the Canadian Dental Association, 2009, v. 75, n. 10, p. 707
By:
- Yarmolinsky, James;
- Ratnapalan, Savithiri;
- Kenny, David J.
Publication type:
Article
RE: Exploring the cross-cancer effect of circulating proteins and discovering potential intervention targets for 13 site-specific cancers.
Published in:
JNCI: Journal of the National Cancer Institute, 2024, v. 116, n. 5, p. 764, doi. 10.1093/jnci/djae064
By:
- Yarmolinsky, James;
- Tzoulaki, Ioanna;
- Gunter, Marc J;
- Travis, Ruth C;
- Smith, George Davey;
- Smith-Byrne, Karl
Publication type:
Article
Circulating Selenium and Prostate Cancer Risk: A Mendelian Randomization Analysis.
Published in:
2018
By:
- Yarmolinsky, James;
- Bonilla, Carolina;
- Haycock, Philip C;
- Langdon, Ryan J Q;
- Lotta, Luca A;
- Langenberg, Claudia;
- Relton, Caroline L;
- Lewis, Sarah J;
- Evans, David M;
- Consortium, PRACTICAL;
- PRACTICAL Consortium;
- Davey Smith, George;
- Martin, Richard M
Publication type:
journal article

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