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- Title
The synthesis and tuberculostatic activity of benzenesulfonohydrazide derivatives.
- Authors
Wisterowicz, Krystyna; Gobis, Katarzyna; Foks, Henryk; Augustynowicz-Kopeć, Ewa
- Abstract
The series of novel N′-aminocarbonothioyl-benzenesulfonohydrazides were synthesized in a reaction of benzenesulphonyl chlorides with various aminocarbothiohydrazides. The structures were confirmed by IR and NMR spectra as well as elemental analysis. All of the obtained compounds were screened in vitro for their tuberculostatic activity. Preliminary results indicated that some target compounds exhibited promising results, especially toward Mycobacterium tuberculosis (Mtb) resistant strain 210. © 2011 Wiley Periodicals, Inc. Heteroatom Chem 23:99-104, 2012; View this article online at . DOI 10.1002/hc.20743
- Publication
Heteroatom Chemistry, 2012, Vol 23, Issue 1, p99
- ISSN
1042-7163
- Publication type
Article
- DOI
10.1002/hc.20743