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- Title
Chemoselective double Michael addition: synthesis of 2,6-diarylspiro[cyclohexane-1,3'-indoline]-2',4-diones via addition of indolin-2-one to divinyl ketones.
- Authors
Zheng Li; Jiasheng Li; Jingya Yang
- Abstract
Seventeen examples of 2,6-diarylspiro[cyclohexane-1,3'-indoline]-2',4-diones were efficiently prepared by the Cs2CO3-catalysed chemoselective double Michael additions of indolin-2-one to divinyl ketones. This method has the advantage of high chemoselectivity, mild reaction conditions, high yield and atom- and step-economy.
- Subjects
CYCLOHEXANE derivatives; INDOLINONE; KETONE derivatives; CHEMOSELECTIVITY; KETOACIDOSIS; OXO compounds
- Publication
Journal of Chemical Research, 2017, Vol 41, Issue 3, p168
- ISSN
1747-5198
- Publication type
Article
- DOI
10.3184/174751917X14878812592779