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- Title
Effects of Copper Oxide Nanoparticles on Antioxidant Enzyme Activities and on Tissue Accumulation of Oreochromis niloticus.
- Authors
Tunçsoy, Mustafa; Duran, Servet; Ay, Özcan; Cicik, Bedii; Erdem, Cahit
- Abstract
Accumulation of copper oxide nanoparticles (CuO NPs) in gill, liver and muscle tissues of Oreochromis niloticus and its effects on superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) activities in gill and liver tissues were studied after exposing the fish to 20 µg/L Cu over 15 days. Copper levels and enzyme activities in tissues were determined using spectrophotometric (ICP-AES and UV) techniques respectively. No mortality was observed during the experiments. Copper levels increased in gill and liver tissues of O. niloticus compared to control when exposed to CuO NPs whereas exposure to metal had no effect on muscle level at the end of the exposure period. Highest accumulation of copper was observed in liver while no accumulation was detected in muscle tissue. SOD, CAT activities decreased and GPx activity increased in gill and liver tissues when exposed to CuO NPs.
- Subjects
NILE tilapia; COPPER oxide; PHYSIOLOGICAL effects of nanoparticles; BIOACCUMULATION in fishes; ANTIOXIDANTS; GLUTATHIONE peroxidase; PHYSIOLOGY
- Publication
Bulletin of Environmental Contamination & Toxicology, 2017, Vol 99, Issue 3, p360
- ISSN
0007-4861
- Publication type
Article
- DOI
10.1007/s00128-017-2129-z