We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Palladium-Catalyzed Suzuki-Miyaura Coupling Reactions of Boronic Acid Derivatives with Aryl Chlorides.
- Authors
Zhou, Zihong; Zhang, Yaqi; Xia, Wang; ChEN, Huixuan; Liang, Hao; He, XuefENg; Yu, Sifan; Cao, Rihui; Qiu, Liqin
- Abstract
A series of new biphenyl N,P-monophosphine ligands L have been developed by introduction of two methoxy groups to the biphenyl backbone. The ligands were found to be much more effective than their counterpart Buchwald ligands in Suzuki-Miyaura coupling reactions of sterically hindered and electron-rich aryl chlorides with aryl boronic acids. A variety of tri- ortho-substituted or tetra- ortho-substituted biaryls or hetero-biaryls were conveniently prepared in up to 99 % yield by using L1-[Pd2(dba)3] (dba=dibenzylideneacetone) as the catalyst.
- Subjects
PALLADIUM catalysts; SUZUKI reaction; BORONIC acid derivatives
- Publication
Asian Journal of Organic Chemistry, 2016, Vol 5, Issue 10, p1260
- ISSN
2193-5807
- Publication type
Article
- DOI
10.1002/ajoc.201600319