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- Title
Type 2 diabetes is associated with low muscle mass in older adults.
- Authors
Kim, Kyung‐Soo; Park, Kyung‐Sun; Kim, Moon‐Jong; Kim, Soo‐Kyung; Cho, Yong‐Wook; Park, Seok Won
- Abstract
Aims Our aim was to clarify the association between type 2 diabetes and the risk of low muscle mass in older adults. Methods In the present study, 414 adults aged 65 years or older (144 patients with type 2 diabetes and 270 control participants) were included. Body composition was measured by dual-energy X-ray absorptiometry. Low muscle mass was defined as the appendicular skeletal muscle mass/height2 ( ASM/Ht2) or appendicular skeletal muscle mass/weight ( ASM/ Wt) of <2 SD below the sex-specific normal mean of the young reference group, or <lower 20th percentile of total body skeletal muscle mass/weight ( TSM/ Wt) from control participants. Results Older men with type 2 diabetes showed significantly lower appendicular skeletal muscle mass than those without diabetes (19.5 ± 3.5 kg vs 21.0 ± 2.8 kg, P < 0.001). The prevalence of low muscle mass was consistently higher in older men with diabetes than those without diabetes defined by ASM/ Ht2 (57.6% vs 41.5%, P = 0.040), ASM/ Wt (23.7% vs 12.3%, P = 0.046) and TSM/ Wt (49.2% vs 20.0%, P < 0.001). In older women with diabetes, the prevalence of low muscle mass was higher than those without diabetes by ASM/ Wt (25.9% vs 15.0%, P = 0.044) and TSM/ Wt (32.9% vs 20.0%, P = 0.030), but not by ASM/ Ht2 (7.1% vs 8.6%, P = 0.685). The risk of low muscle mass was approximately two- to fourfold higher in older adults with type 2 diabetes, even after adjusting for age, body mass index, current smoking and other risk factors. Conclusions In Korean older adults, type 2 diabetes is associated with low muscle mass. Geriatr Gerontol Int 2014; 14 (Suppl. 1): 115-121.
- Subjects
ANTHROPOMETRY; BODY composition; CHI-squared test; CONFIDENCE intervals; EPIDEMIOLOGY; CARDIAC contraction; MUSCULAR atrophy; TYPE 2 diabetes; T-test (Statistics); TRIGLYCERIDES; LOGISTIC regression analysis; DATA analysis; BODY mass index; DISEASE prevalence; DATA analysis software; SKELETAL muscle; WAIST circumference; DESCRIPTIVE statistics; PHOTON absorptiometry; OLD age
- Publication
Geriatrics & Gerontology International, 2014, Vol 14, p115
- ISSN
1444-1586
- Publication type
Article
- DOI
10.1111/ggi.12189