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- Title
Primer Nokturnal Enürezisli Çocuklarda Renal Tubuler Fonksiyonlar.
- Authors
Kalman, Süleyman; Sakallıoğlu, Onur; Kesik, Vural; Faysal, Gök
- Abstract
Introduction: The etiology of primary nocturnal enuresis (PNE) is multifactorial. The effects of genetic and hormonal factors sleep disorders, and bladder dysfunction have been claimed. The other factors include increased urine production at night and impairment of the circadian rhythm of antidiuretic hormone. Aim: To investigate renal tubular functions in children with PNE. Methods: Forty patients with PNE were included in the study. Urine density, FENa, FEK and TRP were analyzed in daytime and nighttime urine. Results: The mean nighttime urine density was 1020.12±7.38 and the mean daytime urine density was 1013.20±7.11 (p<0.05). There was no significant difference between daytime and nighttime values of FENa (0.50±0.48 vs. 0.38±0.33), FEK (2.78±1.04 vs. 2.76±1.52) and TRP (88.5±2.4 vs 86.7±2.8) (p>0.05). Conclusion: Urine density in children with PNE was lower at night. However, there was no difference in of FENa, FEK and TRP . Further studies are needed in order to investigate renal tubular functions in children with PNE.
- Subjects
RENAL tubular transport disorders; ENURESIS; PEDIATRIC research; SLEEP disorders; BLADDER diseases; VASOPRESSIN; URINE; PATIENTS; DIAGNOSIS; THERAPEUTICS
- Publication
Medical Bulletin of Haseki / Haseki Tip Bulteni, 2012, Vol 50, Issue 1, p10
- ISSN
1302-0072
- Publication type
Article