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- Title
The polymorphisms of LYRM1 gene and their association with body measurement and ultrasound traits of Qinchuan cattle.
- Authors
Li, Yaokun; Gao, Jianbin; Yang, Ning; Fu, Changzhen; Cheng, Gong; Wang, Hongbao; Zan, Linsen
- Abstract
Body measurement and meat quality traits which play important roles in the assessment of productivity and economy in cattle were influenced by genes and environmental factors. Latest studies showed that LYR motif containing 1 (LYRM1) may be involved in influencing fatness deposition in animals. The objective of this study was to detect bovine LYRM1 gene polymorphism and analyze its association with body measurement and meat quality traits of cattle. Blood samples were taken from a total of 404 Qinchuan cattle aged from 18-24 months. Created restriction site-polymerase chain reaction-restriction fragment length polymorphism (CRS-PCR-RFLP) and DNA sequencing were used to find out LYRM1 single polymorphism nucleotide (SNPs). Sequence analysis of LYRM1 gene revealed two SNPs (g.165 C > A, g.193 A > G) in 3′ untranslated region (3′UTR) of exon 3. And g.165 C > A showed two genotypes namely AC and CC while g.193 A > G showed three genotypes: AA, AG and GG. Analysis results showed that there were significant associations between polymorphism of these two and body measurement and meat quality traits in Qinchuan cattle population. Based on the results obtained from this study, it is inferred that LYRM1 gene may have potential effects on body measurement and meat quality traits in Qinchuan cattle population and could be used for marker-assisted selection.
- Subjects
GENETIC polymorphisms; GENETIC polymorphism research; CATTLE genetics; POLYMERASE chain reaction; DNA polymerases; SEQUENCE analysis; CATTLE
- Publication
Molecular Biology Reports, 2013, Vol 40, Issue 2, p1511
- ISSN
0301-4851
- Publication type
Article
- DOI
10.1007/s11033-012-2195-6