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- Title
射血分数保留左心疾病相关肺动脉高压患者的临床特征和危险因素分析.
- Authors
冯克福; 储莉; 王德超; 王月平; 闻伟; 马礼坤
- Abstract
Objective To analyze the clinical features and risk factors of patients with left heart disease-associated pulmonary hypertension with ejection fraction preservation (PH-HFpEF), and to evaluate the diagnostic value of echocardiography and clinical features in patients with PH-HFpEF with ejection fraction preservation. Methods A total of 249 patients who received right heart catheterization from January 2021 to December 2022 in the Department of Cardiovascular Medicine of the First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital) were enrolled, including 41 patients with arterial pulmonary hypertension (PAH group) and 39 patients with PH-HFpEF (PH-HFpEF group). The clinical characteristics, echocardiography and right cardiac catheterization data of the two groups were collected. Paired t-test and pearson correlation analysis were performed for the pulmonary artery systolic pressure (Echo-sPAP) detected by echocardiography and the pulmonary artery systolic pressure (RHC-sPAP) detected by right cardiac catheter. Univariate and multivariate logistic regression were used to analyze the clinical characteristics and echocardiography data of the two groups patients, and to determine the clinical factors and echocardiographic indicators for the diagnosis of PH-HFpEF. Cut-off values were calculated by receiver operating characteristic (ROC) curve, and sensitivity and specificity were calculated. Results Echo-sPAP was positively correlated with RHC-sPAP (r=0. 794, P<0. 001). Univariate and multivariate logistic regression analysis showed that the anterior and posterior diameter of left atrial (LAD) and cardiovascular risk factors were independent predictors of the diagnosis of PH-HFpEF. ROC curve results showed that the optimal cut-off value predicted by LAD was 41. 5 mm and the area under the curve was 0. 945. The sensitivity and specificity diagnosing PH-HFpEF patients by combining cardiovascular disease risk factors and LAD>41. 5 mm were 94. 87% and 97. 44%, respectively. Conclusions Echo-sPAP and RHC-sPAP have a good correlation. The combination of LAD>41. 5 mm and cardiovascular risk factors is helpful in the diagnosis of patients with PH-HFpEF.
- Publication
Chinese Journal of Clinical Healthcare, 2023, Vol 26, Issue 4, p522
- ISSN
1672-6790
- Publication type
Article
- DOI
10.3969/J.issn.1672-6790.2023.04.020