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- Title
Rapid Detection of Human Cytomegalovirus and Herpesvirus Hominis IgM Antibody by the Immunoperoxidase Technique.
- Authors
Gerna, Giuseppe; Chambers, Robert W.
- Abstract
Immunoglobulin M (IgM) to human cytomegalovirus (CMV) and herpesvirus hominis (HVH, types 1 and 2) has been searched for in a group of patients with congenital and recent CMV and HVH infections and also in a group of patients with remote CMV and recurrent HVH infections, using the immunoperoxidase antibody technique (IPA) as compared to a technique using sucrose density gradient differential centrifugation. Both techniques detected the same positive samples. High IgM antibody titers (1:32-1:512) were observed in all cases of primary CMV and HVH infection, whereas low titers (1:8-1:16) were found in congenital infections. The IPA technique is sensitive, specific and useful for rapid diagnosis of recent and congenital CMV and HVH infections. Copyright © 1977 S. Karger AG, Basel
- Publication
Intervirology, 1977, Vol 8, Issue 5, p257
- ISSN
0300-5526
- Publication type
Article
- DOI
10.1159/000148901