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Synthetic shRNAs as potent RNAi triggers.
Published in:
Nature Biotechnology, 2005, v. 23, n. 2, p. 227, doi. 10.1038/nbt1052
By:
- Siolas, Despina;
- Lerner, Cara;
- Burchard, Julja;
- Ge, Wei;
- Linsley, Peter S.;
- Paddison, Patrick J.;
- Hannon, Gregory J.;
- Cleary, Michele A.
Publication type:
Article
Second-generation shRNA libraries covering the mouse and human genomes.
Published in:
Nature Genetics, 2005, v. 37, n. 11, p. 1281, doi. 10.1038/ng1650
By:
- Silva, Jose M.;
- Li, Mamie Z.;
- Chang, Ken;
- Wei Ge;
- Golding, Michael C.;
- Rickles, Richard J.;
- Siolas, Despina;
- Hu, Guang;
- Paddison, Patrick J;
- Schlabach, Michael R;
- Sheth, Nihar;
- Bradshaw, Jeff;
- Burchard, Julia;
- Kulkarni, Amit;
- Cavet, Guy;
- Sachidanandam, Ravi;
- McCombie, W. Richard;
- Cleary, Michele A.;
- Elledge, Stephen J.;
- Hannon, Gregory J.
Publication type:
Article
Disruption of an imprinted gene cluster by a targeted chromosomal translocation in mice.
Published in:
Nature Genetics, 2001, v. 29, n. 1, p. 78, doi. 10.1038/ng715
By:
- Cleary, Michele A.;
- van Raamsdonk, Catherine D.;
- Levorse, John;
- Zheng, Binhai;
- Bradley, Allan;
- Tilghman, Shirley M.
Publication type:
Article
Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis.
Published in:
Nature Methods, 2004, v. 1, n. 3, p. 241, doi. 10.1038/nmeth724
By:
- Cleary, Michele A.;
- Kilian, Kristopher;
- Yanqun Wang;
- Bradshaw, Jeff;
- Cavet, Guy;
- Wei Ge;
- Kulkarni, Amit;
- Paddison, Patrick J.;
- Chang, Kenneth;
- Sheth, Nihar;
- Leproust, Eric;
- Coffey, Ernest M.;
- Burchard, Julja;
- McCombie, W. Richard;
- Linsley, Peter;
- Hannon, Gregory J.
Publication type:
Article
Cloning of short hairpin RNAs for gene knockdown in mammalian cells.
Published in:
Nature Methods, 2004, v. 1, n. 2, p. 163, doi. 10.1038/nmeth1104-163
By:
- Paddison, Patrick J.;
- Cleary, Michele;
- Silva, Jose Maria;
- Chang, Kenneth;
- Sheth, Nihar;
- Sachidanandam, Ravi;
- Hannon, Gregory J.
Publication type:
Article
Integrative ChIP-seq/Microarray Analysis Identifies a CTNNB1 Target Signature Enriched in Intestinal Stem Cells and Colon Cancer.
Published in:
PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0092317
By:
- Watanabe, Kazuhide;
- Biesinger, Jacob;
- Salmans, Michael L.;
- Roberts, Brian S.;
- Arthur, William T.;
- Cleary, Michele;
- Andersen, Bogi;
- Xie, Xiaohui;
- Dai, Xing
Publication type:
Article
Gene Signatures Derived from a c-MET-Driven Liver Cancer Mouse Model Predict Survival of Patients with Hepatocellular Carcinoma.
Published in:
PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024582
By:
- Ivanovska, Irena;
- Chunsheng Zhang;
- Angela M. Liu;
- Kwong F. Wong;
- Lee, Nikki P.;
- Lewis, Patrick;
- Philippar, Ulrike;
- Bansal, Dimple;
- Buser, Carolyn;
- Scott, Martin;
- Mao, Mao;
- Poon, Ronnie T. P.;
- Fan, Sheung Tat;
- Cleary, Michele A.;
- Luk, John M.;
- Dai, Hongyue
Publication type:
Article
Predictive Genes in Adjacent Normal Tissue Are Preferentially Altered by sCNV during Tumorigenesis in Liver Cancer and May Rate Limiting.
Published in:
PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0020090
By:
- Lamb, John R.;
- Zhang, Chunsheng;
- Xie, Tao;
- Wang, Kai;
- Zhang, Bin;
- Hao, Ke;
- Chudin, Eugene;
- Fraser, Hunter B.;
- Millstein, Joshua;
- Ferguson, Mark;
- Suver, Christine;
- Ivanovska, Irena;
- Scott, Martin;
- Philippar, Ulrike;
- Bansal, Dimple;
- Zhang, Zhan;
- Burchard, Julja;
- Smith, Ryan;
- Greenawalt, Danielle;
- Cleary, Michele
Publication type:
Article
A Lentivirus-Mediated Genetic Screen Identifies Dihydrofolate Reductase (DHFR) as a Modulator of β- Catenin/GSK3 Signaling.
Published in:
PLoS ONE, 2009, v. 4, n. 9, p. 1, doi. 10.1371/journal.pone.0006892
By:
- Klinghoffer, Richard A.;
- Frazier, Jason;
- Annis, James;
- Berndt, Jason D.;
- Roberts, Brian S.;
- Arthur, William T.;
- Lacson, Raul;
- Zhang, Xiaohua Douglas;
- Ferrer, Marc;
- Moon, Randall T.;
- Cleary, Michele A.
Publication type:
Article
In vivo isotopically labeled atherosclerotic aorta plaques in ApoE KO mice and molecular profiling by matrix-assisted laser desorption/ionization mass spectrometric imaging.
Published in:
Rapid Communications in Mass Spectrometry: RCM, 2014, v. 28, n. 22, p. 2471, doi. 10.1002/rcm.7039
By:
- Castro‐Perez, Jose;
- Hatcher, Nathan;
- Kofi Karikari, Nana;
- Wang, Sheng‐Ping;
- Mendoza, Vivienne;
- Shion, Henry;
- Millar, Alan;
- Shockcor, John;
- Towers, Mark;
- McLaren, David;
- Shah, Vinit;
- Previs, Stephen;
- Akinsanya, Karen;
- Cleary, Michele;
- Roddy, Thomas P.;
- Johns, Douglas G.
Publication type:
Article
Determination of low levels of <sup>2</sup>H-labeling using high-resolution mass spectrometry: Application in studies of lipid flux and beyond.
Published in:
Rapid Communications in Mass Spectrometry: RCM, 2014, v. 28, n. 3, p. 239, doi. 10.1002/rcm.6776
By:
- Herath, Kithsiri B.;
- Zhong, Wendy;
- Yang, Jiong;
- Mahsut, Ablatt;
- Rohm, Rory J.;
- Shah, Vinit;
- Castro‐Perez, Jose;
- Zhou, Haihong;
- Attygalle, Athula B.;
- Kang, Ling;
- Singh, Sheo;
- Johns, Douglas G.;
- Cleary, Michele A.;
- Hubbard, Brian K.;
- Previs, Stephen F.;
- Roddy, Thomas P.
Publication type:
Article
Rapid detection and quantification of apolipoprotein L1 genetic variants and total levels in plasma by ultra-performance liquid chromatography/tandem mass spectrometry.
Published in:
Rapid Communications in Mass Spectrometry: RCM, 2013, v. 27, n. 23, p. 2639, doi. 10.1002/rcm.6734
By:
- Zhou, Haihong;
- Hoek, Maarten;
- Yi, Pan;
- Rohm, Rory J.;
- Mahsut, Ablatt;
- Brown, Patricia;
- Saunders, Jason;
- Chmielowski, Rebecca A.;
- Ren, Ning;
- Shuster, Dan;
- Southwick, Katie;
- Ayanoglu, Gulesi;
- Gorman, Dan;
- Laface, Drake;
- Santino, Salvatore;
- Conway, James;
- Liu, Zhong;
- Cully, Doris;
- Cleary, Michele;
- Roddy, Thomas P.
Publication type:
Article
Measurement of apo(a) kinetics in human subjects using a microfluidic device with tandem mass spectrometry.
Published in:
Rapid Communications in Mass Spectrometry: RCM, 2013, v. 27, n. 12, p. 1294, doi. 10.1002/rcm.6572
By:
- Zhou, Haihong;
- Castro‐Perez, Jose;
- Lassman, Michael E.;
- Thomas, Tiffany;
- Li, Wenyu;
- McLaughlin, Theresa;
- Dan, Xie;
- Jumes, Patricia;
- Wagner, John A.;
- Gutstein, David E.;
- Hubbard, Brian K.;
- Rader, Daniel J.;
- Millar, John S.;
- Ginsberg, Henry N.;
- Reyes‐Soffer, Gissette;
- Cleary, Michele;
- Previs, Stephen F.;
- Roddy, Thomas P.
Publication type:
Article
A microRNA component of the p53 tumour suppressor network.
Published in:
Nature, 2007, v. 447, n. 7148, p. 1130, doi. 10.1038/nature05939
By:
- Lin He;
- Xingyue He;
- Lim, Lee P.;
- de Stanchina, Elisa;
- Zhenyu Xuan;
- Yu Liang;
- Wen Xue;
- Zender, Lars;
- Magnus, Jill;
- Ridzon, Dana;
- Jackson, Aimee L.;
- Linsley, Peter S.;
- Chen, Caifu;
- Lowe, Scott W.;
- Cleary, Michele A.;
- Hannon, Gregory J.
Publication type:
Article
A 1,536-Well Ultra-High-Throughput siRNA Screen to Identify Regulators of the Wnt/β-Catenin Pathway.
Published in:
Assay & Drug Development Technologies, 2010, v. 8, n. 3, p. 286, doi. 10.1089/adt.2009.0262
By:
- Namjin Chung;
- Shane Marine;
- Emily A. Smith;
- Robert Liehr;
- S. Todd Smith;
- Louis Locco;
- Edward Hudak;
- Anthony Kreamer;
- Alison Rush;
- Brian Roberts;
- Michael B. Major;
- Randall T. Moon;
- William Arthur;
- Michele Cleary;
- Berta Strulovici;
- Marc Ferrer
Publication type:
Article
An Optimized Lentivirus-Mediated RNAi Screen Reveals Kinase Modulators of Kinesin-5 Inhibitor Sensitivity.
Published in:
Assay & Drug Development Technologies, 2008, v. 6, n. 1, p. 105, doi. 10.1089/adt.2007.106
By:
- Richard A. Klinghoffer;
- Brian Roberts;
- James Annis;
- Jason Frazier;
- Patrick Lewis;
- Peter S. Linsley;
- Michele A. Cleary
Publication type:
Article
A resource for large-scale RNA-interference-based screens in mammals.
Published in:
Nature, 2004, v. 428, n. 6981, p. 427, doi. 10.1038/nature02370
By:
- Paddison, Patrick J.;
- Silva, Jose M.;
- Conklin, Douglas S.;
- Schlabach, Mike;
- Li, Mamie;
- Aruleba, Shola;
- Balija, Vivekanand;
- O'Shaughnessy, Andy;
- Gnoj, Lidia;
- Scobie, Kim;
- Chang, Kenneth;
- Westbrook, Thomas;
- Cleary, Michele;
- Sachidanandam, Ravi;
- McCombie, W. Richard;
- Elledge, Stephen J.;
- Hannon, Gregory J.
Publication type:
Article
Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice.
Published in:
Mammalian Genome, 2009, v. 20, n. 8, p. 476, doi. 10.1007/s00335-009-9217-2
By:
- Enpeng Zhao;
- Keller, Mark P.;
- Rabaglia, Mary E.;
- Oler, Angie T.;
- Stapleton, Donnie S.;
- Schueler, Kathryn L.;
- Neto, Elias Chaibub;
- Jee Young Moon;
- Ping Wang;
- I-Ming Wang;
- Pek Yee Lum;
- Ivanovska, Irena;
- Cleary, Michele;
- Greenawalt, Danielle;
- John Tsang;
- Choi, Youn Jeong;
- Kleinhanz, Robert;
- Shang, Jin;
- Yun-Ping Zhou;
- Howard, Andrew D.
Publication type:
Article
Synthetic lethality of PARP inhibition in BRCA-network disrupted tumor cells is associated with interferon pathway activation and enhanced by interferon-γ.
Published in:
Apoptosis, 2012, v. 17, n. 7, p. 691, doi. 10.1007/s10495-012-0707-4
By:
- Warrener, Paul;
- Kim, Sammy;
- Williams, Sybil;
- Biery, Matthew;
- Gordon, Marcia;
- Toniatti, Carlo;
- Cleary, Michele;
- Linsley, Peter;
- Carleton, Michael
Publication type:
Article
Bruton's Tyrosine Kinase Revealed as a Negative Regulator of Wnt-β-Catenin Signaling.
Published in:
Science Signaling, 2009, v. 2, n. 72, p. 1, doi. 10.1126/scisignal.2000230
By:
- James, Richard G.;
- Biechele, Travis L.;
- Conrad, William H.;
- Camp, Nathan D.;
- Fass, Daniel M.;
- Major, Michael B.;
- Sommer, Karen;
- Yi, XianHua;
- Roberts, Brian S.;
- Cleary, Michele A.;
- Arthur, William T.;
- MacCoss, Michael;
- Rawlings, David J.;
- Haggarty, Stephen J.;
- Moon, Randall T.
Publication type:
Article
New Regulators of Wnt/β-Catenin Signaling Revealed by Integrative Molecular Screening.
Published in:
Science Signaling, 2008, v. 1, n. 45, p. 1, doi. 10.1126/scisignal.2000037
By:
- Major, Michael B.;
- Roberts, Brian S.;
- Berndt, Jason D.;
- Marine, Shane;
- Anastas, Jamie;
- Chung, Namjin;
- Ferrer, Marc;
- XianHua Yi;
- Stoick-Cooper, Cristi L.;
- Haller, Priska D. von;
- Kategaya, Lorna;
- Chien, Andy;
- Angers, Stephane;
- MacCoss, Michael;
- Cleary, Michele A.;
- Arthur, William T.;
- Moon, Randall T.
Publication type:
Article

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