We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Human Cytomegalovirus (HCMV) DNAemia in the Mother at Amniocentesis as a Risk Factor for Tatrogenic HCMV Infection of the Fetus.
- Authors
Revello, Maria Grazia; Furione, Milena; Zavattoni, Maurizio; Tassis, Beatrice; Nicolini, Umberto; Fabbri, Elisa; Gerna, Giuseppe
- Abstract
To investigate whether invasive procedures performed in the presence of human cytomegalovirus (HCMV) DNA in maternal peripheral blood (HCMV DNAemia) represent a risk for iatrogenic transmission of HCMV infection to the fetus, 194 pregnant women undergoing prenatal diagnosis because of a primary HCMV infection and their 199 fetuses were investigated. Overall, 27 (37%) of 73 mothers of uninfected fetuses and 22 (37%) of 59 mothers of infected fetuses were HCMV DNAemia-positive at amniocentesis. Of the 8 mothers of the 8 fetuses with false-negative amniocentesis results, 4 were DNAemia-positive and 4 were DNAemia-negative at amniocentesis. Therefore, maternal HCMV DNAemia is not a significant risk factor for iatrogenic HCMV transmission to the fetus during amniocentesis.
- Subjects
CYTOMEGALOVIRUSES; AMNIOCENTESIS; DIAGNOSIS of fetal diseases; HERPESVIRUSES; DNA viruses; PRENATAL diagnosis
- Publication
Journal of Infectious Diseases, 2008, Vol 197, Issue 4, p593
- ISSN
0022-1899
- Publication type
Article
- DOI
10.1086/526499