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Insights into the changes in the proteome of Alzheimer disease elucidated by a meta-analysis.
- Published in:
- Scientific Data, 2021, v. 8, n. 1, p. 1, doi. 10.1038/s41597-021-01090-8
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- Article
Microdissected Pyramidal Cell Proteomics of Alzheimer Brain Reveals Alterations in Creatine Kinase B-Type, 14-3-3-γ, and Heat Shock Cognate 71.
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- Frontiers in Aging Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnagi.2021.735334
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- Publication type:
- Article
Live Cell FRET Imaging Reveals Amyloid β-Peptide Oligomerization in Hippocampal Neurons.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4530, doi. 10.3390/ijms22094530
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- Article
INTRANEURONAL AMYLOID β-PEPTIDE LEVELS ARE AFFECTED BY MONOAMINE OXIDASE B.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P682, doi. 10.1016/j.jalz.2017.06.849
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- Article
GAMMA-SECRETASE IS PRESENT AT BOTH SIDES OF THE NEURONAL SYNAPSE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1041, doi. 10.1016/j.jalz.2016.06.2163
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- Article
Adam10 and bace1 are localized to synaptic vesicles.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P363, doi. 10.1016/j.jalz.2015.06.262
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- Article
Affinity pulldown of gamma-secretase and associated proteins from human and rat brain
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- 2010
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- Publication type:
- Abstract
Affinity purification of gamma-secretase associated proteins in synaptic membranes and synaptic vesicles
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- 2010
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- Abstract
Gamma-secretase–associated proteins in detergent resistant membranes from brain
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- 2010
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- Abstract
A highly sensitive ELISA reveals intracellular accumulation of Aβ42 in microdissected human Purkinje neurons from Alzheimer brains
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- 2010
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- Abstract
P4-202: Active γ-secretase is localized to detergent resistant membranes in human brain
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- 2008
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- Abstract
P3-328: Cleavage of endogenous substrates by γ-secretase in rat brain membranes
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- 2008
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- Abstract
P1-469: Long amyloid-β peptide variants in Alzheimer's disease brains
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- 2008
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- Abstract
P1-451: The oligomerization of amyloid-β peptide
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- 2008
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- Abstract
P3-414: Characterization of γ-secretase activity in rat brain
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- 2006
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- Abstract
P3-414: Characterization of γ-secretase activity in rat brain
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- 2006
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- Abstract
Collagenous Alzheimer amyloid plaque componentassembles amyloid fibrils into protease resistantaggregates.
- Published in:
- FEBS Journal, 2005, v. 272, n. 9, p. 2231, doi. 10.1111/j.1742-4658.2005.04647.x
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- Publication type:
- Article
Macroautophagy -- a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease.
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- Journal of Cell Biology, 2005, v. 171, n. 1, p. 87, doi. 10.1083/jcb.200505082
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- Publication type:
- Article
Super-resolution microscopy reveals γ- secretase at both sides of the neuronal synapse.
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- Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0296-5
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- Article
Visualizing Active Enzyme Complexes Using a Photoreactive Inhibitor for Proximity Ligation – Application on γ-Secretase
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- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063962
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- Article
The Pathogenic Aβ43 Is Enriched in Familial and Sporadic Alzheimer Disease.
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- PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0055847
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- Article
γ-Secretase Dependent Production of Intracellular Domains Is Reduced in Adult Compared to Embryonic Rat Brain Membranes.
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- PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009772
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- Article
Synaptic and Endosomal Localization of Active γ-Secretase in Rat Brain.
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- PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008948
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- Article
The N‐glycan profile in cortex and hippocampus is altered in Alzheimer disease.
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- Journal of Neurochemistry, 2021, v. 159, n. 2, p. 292, doi. 10.1111/jnc.15202
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- Article
Loss of neprilysin alters protein expression in the brain of Alzheimer's disease model mice.
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- Proteomics, 2015, v. 15, n. 19, p. 3349, doi. 10.1002/pmic.201400211
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- Article
What Can N-glycomics and N-glycoproteomics of Cerebrospinal Fluid Tell Us about Alzheimer Disease?
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- Biomolecules (2218-273X), 2021, v. 11, n. 6, p. 858, doi. 10.3390/biom11060858
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- Article
The PSEN1 I143T mutation in a Swedish family with Alzheimer's disease: clinical report and quantification of Aβ in different brain regions.
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- European Journal of Human Genetics, 2010, v. 18, n. 11, p. 1202, doi. 10.1038/ejhg.2010.107
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- Article
Glycan biomarkers for Alzheimer disease correlate with T‐tau and P‐tau in cerebrospinal fluid in subjective cognitive impairment.
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- FEBS Journal, 2020, v. 287, n. 15, p. 3221, doi. 10.1111/febs.15197
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- Article
Cover Feature: Engineered Human Induced Pluripotent Cells Enable Genetic Code Expansion in Brain Organoids (ChemBioChem 22/2021).
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- ChemBioChem, 2021, v. 22, n. 22, p. 3108, doi. 10.1002/cbic.202100501
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- Article
Engineered Human Induced Pluripotent Cells Enable Genetic Code Expansion in Brain Organoids.
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- ChemBioChem, 2021, v. 22, n. 22, p. 3208, doi. 10.1002/cbic.202100399
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- Article
Conformation‐specific antibodies against multiple amyloid protofibril species from a single amyloid immunogen.
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- Journal of Cellular & Molecular Medicine, 2019, v. 23, n. 3, p. 2103, doi. 10.1111/jcmm.14119
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- Article
Analysis of microdissected neurons by <sup>18</sup>O mass spectrometry reveals altered protein expression in Alzheimer's disease.
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- Journal of Cellular & Molecular Medicine, 2012, v. 16, n. 8, p. 1686, doi. 10.1111/j.1582-4934.2011.01441.x
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- Publication type:
- Article
γ-secretase complexes containing caspase-cleaved presenilin-1 increase intracellular Aβ<sub>42</sub>/Aβ<sub>40</sub> ratio.
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- Journal of Cellular & Molecular Medicine, 2011, v. 15, n. 10, p. 2150, doi. 10.1111/j.1582-4934.2010.01208.x
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- Publication type:
- Article
Affinity pulldown of γ-secretase and associated proteins from human and rat brain.
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- Journal of Cellular & Molecular Medicine, 2010, v. 14, n. 11, p. 2675, doi. 10.1111/j.1582-4934.2009.00907.x
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- Publication type:
- Article
Gene therapy in Alzheimer’s disease – potential for disease modification.
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- Journal of Cellular & Molecular Medicine, 2010, v. 14, n. 4, p. 741, doi. 10.1111/j.1582-4934.2010.01038.x
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- Publication type:
- Article
Proton myo-inositol cotransporter is a novel γ-secretase associated protein that regulates Aβ production without affecting Notch cleavage.
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- FEBS Journal, 2015, v. 282, n. 17, p. 3438, doi. 10.1111/febs.13353
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- Publication type:
- Article
Human brain proteins showing neuron-specific interactions with γ-secretase.
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- 2015
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- Publication type:
- Editorial
The role of protein glycosylation in Alzheimer disease.
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- FEBS Journal, 2014, v. 281, n. 1, p. 46, doi. 10.1111/febs.12590
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- Publication type:
- Article
Active γ-secretase is localized to detergent-resistant membranes in human brain.
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- FEBS Journal, 2008, v. 275, n. 6, p. 1174, doi. 10.1111/j.1742-4658.2008.06278.x
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- Publication type:
- Article
Monoamine oxidase B is elevated in Alzheimer disease neurons, is associated with γ-secretase and regulates neuronal amyloid β-peptide levels.
- Published in:
- Alzheimer's Research & Therapy, 2017, v. 9, p. 1, doi. 10.1186/s13195-017-0279-1
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- Publication type:
- Article
ADAM10 and BACE1 are localized to synaptic vesicles.
- Published in:
- Journal of Neurochemistry, 2015, v. 135, n. 3, p. 606, doi. 10.1111/jnc.13287
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- Publication type:
- Article
Non-specific Detection of a Major Western Blotting Band in Human Brain Homogenates by a Multitude of Amyloid Precursor Protein Antibodies.
- Published in:
- Frontiers in Aging Neuroscience, 2019, p. 1, doi. 10.3389/fnagi.2019.00273
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- Publication type:
- Article
Analysis of microdissected human neurons by a sensitive ELISA reveals a correlation between elevated intracellular concentrations of Aβ42 and Alzheimer’s disease neuropathology.
- Published in:
- Acta Neuropathologica, 2010, v. 119, n. 5, p. 543, doi. 10.1007/s00401-010-0661-6
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- Publication type:
- Article
Neuronal Trafficking of the Amyloid Precursor Protein—What Do We Really Know?
- Published in:
- Biomedicines, 2021, v. 9, n. 7, p. 801, doi. 10.3390/biomedicines9070801
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- Publication type:
- Article
Lack of N-glycosylation increases amyloidogenic processing of the amyloid precursor protein.
- Published in:
- Glycobiology, 2022, v. 32, n. 6, p. 506, doi. 10.1093/glycob/cwac009
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- Publication type:
- Article
Changed membrane integration and catalytic site conformation are two mechanisms behind the increased Aβ42/Aβ40 ratio by presenilin 1 familial Alzheimer-linked mutations.
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- FEBS Open Bio, 2014, v. 4, p. 393, doi. 10.1016/j.fob.2014.04.006
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- Article
Changed membrane integration and catalytic site conformation are two mechanisms behind the increased Aβ42/Aβ40 ratio by presenilin 1 familial Alzheimer‐linked mutations.
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- FEBS Open Bio, 2014, v. 4, n. 1, p. 393, doi. 10.1016/j.fob.2014.04.006
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- Publication type:
- Article
Aβ42 oligomer-specific antibody ALZ-201 reduces the neurotoxicity of Alzheimer's disease brain extracts.
- Published in:
- Alzheimer's Research & Therapy, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13195-022-01141-1
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- Publication type:
- Article
Aβ43 is more frequent than Aβ40 in amyloid plaque cores from Alzheimer disease brains.
- Published in:
- Journal of Neurochemistry, 2009, v. 110, n. 2, p. 697, doi. 10.1111/j.1471-4159.2009.06170.x
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- Publication type:
- Article
High-Resolution Separation of Amyloid β-Peptides: Structural Variants Present in Alzheimer's Disease Amyloid.
- Published in:
- Journal of Neurochemistry, 1996, v. 67, n. 1, p. 294, doi. 10.1046/j.1471-4159.1996.67010294.x
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- Article