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- Title
Primary extramammary Paget's disease with extensive skeletal metastases.
- Authors
Reddy, Indukooru Subrayalu; Swain, Meenakshi; Gowrishankar, Swarnalata; Murthy, Dronamraju Butchi Narayana
- Abstract
Extramammary Paget's disease (EMPD) is an uncommon malignancy that is most commonly seen in the vulval area in postmenopausal women. Pruritus is the predominant symptom. The clinical presentation can be so nonspecific that it can be misdiagnosed as an inflammatory or infective condition. We report an elderly male patient with EMPD over the pubic area, which remained asymptomatic for 5 years; he presented with severe low backache of 5 months' duration. Skin biopsy and immunohistochemistry showed the typical epidermal changes and deep dermal invasion. Positron emission tomography scan revealed involvement of regional lymph nodes as well as extensive skeletal metastases.
- Subjects
OSTEITIS deformans; BONE metastasis; POSTMENOPAUSE; ITCHING; APOCRINE glands; BACKACHE; CANCER cells; IMMUNOHISTOCHEMISTRY; SKIN tumors; VULVA; MALE reproductive organs; SECONDARY primary cancer; TUMORS
- Publication
Indian Journal of Dermatology, Venereology & Leprology, 2012, Vol 78, Issue 1, p89
- ISSN
0378-6323
- Publication type
journal article
- DOI
10.4103/0378-6323.90954