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- Title
Activation of human bitter taste receptors by polymethoxylated flavonoids.
- Authors
Kuroda, Yuki; Ikeda, Riko; Yamazaki, Toyomi; Ito, Keisuke; Uda, Kazunari; Wakabayashi, Keiji; Watanabe, Tatsuo
- Abstract
Tangeretin and nobiletin are polymethoxylated flavonoids in citrus peel. Both tangeretin and nobiletin are bitter; however, their bitterness has not been evaluated using human bitter taste receptors (hTAS2Rs). We screened 25 kinds of hTAS2Rs and found that hTAS2R14 and hTAS2R46 received both compounds.
- Subjects
PHYSIOLOGICAL effects of flavonoids; CITRUS; BITTERNESS (Taste)
- Publication
Bioscience, Biotechnology & Biochemistry, 2016, Vol 80, Issue 10, p2014
- ISSN
0916-8451
- Publication type
Article
- DOI
10.1080/09168451.2016.1184558