We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Sonodynamic and Photodynamic Therapy in Advanced Breast Carcinoma: A Report of 3 Cases.
- Authors
Xiaohuai Wang; Weimin Zhang; Zhiyong Xu; Yifan Luo; Mitchell, Doug; Moss, Ralph W.
- Abstract
Photodynamic therapy (PDT) is an established therapeutic method, first approved by the FDA for certain kinds of cancer in 1998. There are also increasing data to show that a related procedure, sonodynamic therapy (SDT), is a promising new modality for cancer treatment. Here, the authors report clinical results in 3 advanced refractory breast cancer patients who were treated using a combination of sonodynamic and photodynamic therapy (SPDT), along with conventional therapies. All 3 patients had pathologically proven metastatic breast carcinoma. These widely disseminated carcinomas had ultimately failed to respond to conventional therapy. A new sensitizing agent, Sonoflora 1 ™ (SF1) was administered sublingually; then, after a 24-hour delay, patients were treated with a combination of light and ultrasound. All patients had significant partial or complete responses. SPDT is a promising new therapeutic combination for the treatment of breast cancer.
- Subjects
UNITED States; CLINICAL medicine research; PHOTOCHEMOTHERAPY; UNITED States. Food &; Drug Administration; BREAST cancer treatment; CANCER patients
- Publication
Integrative Cancer Therapies, 2009, Vol 8, Issue 3, p283
- ISSN
1534-7354
- Publication type
Article
- DOI
10.1177/1534735409343693