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- Title
Diagnostic value of time-resolved CT angiography for the lower leg.
- Authors
Sommer WH; Helck A; Bamberg F; Albrecht E; Becker CR; Weidenhagen R; Kramer H; Reiser MF; Nikolaou K; Sommer, Wieland H; Helck, Andreas; Bamberg, Fabian; Albrecht, Edda; Becker, Christoph R; Weidenhagen, Rolf; Kramer, Harald; Reiser, Maximilian F; Nikolaou, Konstantin
- Abstract
<bold>Objective: </bold>The aim of this study was to test the feasibility of time-resolved computed tomography angiography (TR-CTA) for use in the lower leg.<bold>Methods: </bold>Fifty-nine patients with suspected peripheral arterial occlusive disease were examined with a standard CTA (S-CTA) of the lower run-off and with an additional TR-CTA of the calves (12 phases; 2.5 s/phase, 80 kV, 120 mAs, volume of contrast medium 50 mL, flow rate 5.0 mL/s). For seven lower-leg artery segments, arterial contrast and the presence of venous overlay were tested for S-CTA and TR-CTA. Stenoses were classified on a three-point scale separately for S-CTA and TR-CTA, and diagnostic confidence for stenosis assessment was evaluated for both datasets. Contrast arrival times and HU values were evaluated in patients with asymmetric proximal stenoses.<bold>Results: </bold>TR-CTA resulted in significantly higher contrast enhancement (P < 0.0001) and less venous overlay as compared to S-CTA (P < 0.05). Diagnostic confidence for stenosis rating was significantly higher in TR-CTA (P < 0.0001). Asymmetric proximal stenoses lead to significantly delayed and diminished contrast enhancement on the stenotic side.<bold>Conclusion: </bold>TR-CTA of the calves is feasible and provides higher enhancement and higher diagnostic confidence as compared to monophasic CTA of the lower legs.
- Publication
European Radiology, 2010, Vol 20, Issue 12, p2876
- ISSN
0938-7994
- Publication type
journal article
- DOI
10.1007/s00330-010-1861-0