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- Title
Failure to Recover Infective 'Ribonucleic Acid' from Myxovirus Preparations.
- Authors
ADA, G. L.; LIND, PATRICIA E.; LARKIN, LOIS; BURNET, F. M.
- Abstract
IT now seems clear that preparations of infective 'ribonucleic acid' can be obtained from crude preparations of many animal viruses, although Colter et al. have reported failure with Bunyamwera virus preparations1. The technique used in most cases is similar to the treatment introduced by Gierer and Schramm2, namely, exposure of the virus preparation to concentrated phenol. Recognition that the infectivity of the product of phenol treatment is due to a component other than intact virus is based on such criteria as susceptibility to ribonucleases, stability in different media and rate of sedimentation in the ultracentrifuge1,2.
- Publication
Nature, 1959, Vol 184, Issue 4683, p360
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/184360a0