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- Title
The activity in vitro and in vivo of a new imidazole antifungal, ketoconazole.
- Authors
Odds, F. C.; Milne, L. J. R.; Gentles, J. C.; Ball, E. Hazel; Milne, L J; Ball, E H
- Abstract
Ketoconazole, a new water-soluble synthetic imidazole derivative which is absorbed into the bloodstream after oral administration, was inhibitory to a range of pathogenic yeasts and fungi in concentrations from 0.1 to 64 mg/L The drug was effective in the treatment of experimental dermatophytosis in guinea pigs and experimental systemic candidosis in rabbits. It is considered to be of potential value in the treatment of human mycoses.
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 1980, Vol 6, Issue 1, p97
- ISSN
0305-7453
- Publication type
journal article