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- Title
Tumour immunology: Stressed DCs can't handle T cells.
- Authors
Minton, Kirsty
- Abstract
The article discusses tumorigenesis promotion of tumour-associated dendritic cells (tDCs) through activation of antitumuor T cell response. It references the article "ER stress sensor XBP1 controls anti-tumor immunity by disrupting dendritic cell homeostasis," by J. R. Cubillos-Ruiz and colleagues in the 2015 issue of the periodical "Cell." It also explores the results of the research's transcriptional profiling.
- Subjects
DENDRITIC cells; T cells; ENDOPLASMIC reticulum; ANTINEOPLASTIC agents; IMMUNITY; CUBILLOS-Ruiz, J. R.; GENETIC transcription
- Publication
Nature Reviews Immunology, 2015, Vol 15, Issue 8, p465
- ISSN
1474-1733
- Publication type
Article
- DOI
10.1038/nri3885