We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Physical Functioning Among Women Aged 80 Years and Older With Previous Fracture.
- Authors
Crandall, Carolyn J.; Robbins, John A.; LaMonte, Michael J.; Wactawski-Wende, Jean; Snively, Beverly M.; LeBoff, Meryl S.; Cauley, Jane A.; Lewis, Cora E.; Wallace, Robert; Wenjun Li; Zhao Chen; Li, Wenjun; Chen, Zhao
- Abstract
<bold>Background: </bold>The oldest old are the fastest growing segment of the elderly population. Little is known regarding the associations of fracture history with physical functioning assessed after age 80.<bold>Methods: </bold>Among 33,386 women surviving to age 80 years (mean ± SD years 84.6 ± 3.4), we examined the relationship between history of incident fracture after entry into the Women's Health Initiative (follow-up 15.2 ± 1.3 years) and their physical functioning assessed using the RAND-36 instrument most proximal to 2012 end of follow-up.<bold>Results: </bold>Baseline mean (±SD) physical function score was 82 (± 18). After adjustment for demographic and medical characteristics, fracture at each site, including hip, upper limb, lower limb, and central body, was associated with significantly lower subsequent physical functioning (all p < .001). Hip, upper leg, spine, and pelvis fractures were particularly related with lower physical functioning scores, 11.7 (95% CI: 10.3, 13.1), 10.5 (8.8, 12.3), 9.8 (8.9, 10.8), and 8.7 (7.2, 10.2) units lower, respectively, compared with women without fracture (each p < .0001). Compared with women without central site fracture, women with central site fractures also had lower physical functioning scores (10.0 [9.3, 10.8] units lower]; p < .0001). In case-only analysis of fractures, older age, less than 1 year since fracture, one or more additional sites fractured, history of cardiovascular disease or cancer, higher body mass index, and no alcohol intake in the past 3 months also were independent predictors of lower physical functioning score (all p < .05).<bold>Conclusions: </bold>Among women surviving to 80 years and older, prior fracture is associated with lower current physical functioning, regardless of anatomical site of fracture, independent of other major predictors of disability.
- Subjects
UNITED States; FUNCTIONAL assessment of older women; OLDER women; BONE fractures; WOMEN'S health; WOMEN'S Health Initiative (U.S.); HEALTH; PATIENTS; WOUNDS &; injuries; GERIATRIC assessment; AGING; COMPARATIVE studies; FRAIL elderly; HEALTH status indicators; RESEARCH methodology; MEDICAL cooperation; QUALITY of life; QUESTIONNAIRES; RESEARCH; RESEARCH funding; SURVEYS; EVALUATION research
- Publication
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2016, Vol 71, pS31
- ISSN
1079-5006
- Publication type
journal article
- DOI
10.1093/gerona/glv060