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- Title
广西地区 104 例泰国缺失型α-地中海贫血 1 的研究.
- Authors
陈文强; 陈萍; 丘玉铃; 谢湘芝; 肖 璇
- Abstract
Objective: To analyze hematology, genotype, phenotype and ethnic distribution of Thai type deletions thalassemia in Guangxi region. Methods: The outpatient's blood, hemoglobin and -thalassemia genotype was detected and these data were collected and analyzed. Results: 104 cases of Thai type deletions thalassemia were detected, including 71 cases of --Thai/αα, 17 cases of -THAI/-α3.7, 14 cases of --THAI/αCSα, 2 cases of --THAI/αQSα; statistically significant difference were not fund between --THAI/ααand --SEA/ααin blood test, P>0.05, statistically significant difference were found between Thai type deletions Hb H disease (--THAI/-α3.7,--THAI/αCSα, --THAI/αQSα) and Southeast Asia deletions type Hb H disease (--SEA/-α3.7, --SEA/αCSα), P<0.01. The ethnic distribution were found in 67 cases of Zhuang, 34 cases of Han, three cases of other ethnics. Conclusions: Thai type deletions thalassemia has a certain incidence in Guangxi, most of Zhuang people. Compared to Southeast deletions Hb H disease, Thai type deletions Hb H disease (--Thai/αCSα) showed an earlier, severe symptoms of anemia.
- Publication
Progress in Modern Biomedicine, 2015, Vol 15, Issue 24, p4649
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2015.24.012