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- Title
The Impact of Lesion Complexity and the CHA<sub>2</sub>DS<sub>2</sub>-VASc Score on Spontaneous Reperfusion in Patients with ST-Segment Elevation Myocardial Infarction.
- Authors
Alıcı, Gökhan; Barman, Hasan Ali; Atıcı, Adem; Tuğrul, Sevil; Genç, Ömer; Şahin, İrfan
- Abstract
<bold>Background: </bold>In patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI), a patent infarct-related artery (IRA) on initial angiography is defined as spontaneous reperfusion (SR).<bold>Objective: </bold>The present study aimed to determine the impact of lesion complexity and the CHA2DS2-VASc score on SR in patients with STEMI.<bold>Methods: </bold>A total number of 1,641 consecutive patients with STEMI undergoing primary PCI were assessed for this study. Patients were divided into 2 groups, those with SR, SR(+) (n = 239), and those without SR, SR(-) (n = 1402), according to their initial angiography and SR status. CHA2DS2-VASc scores were calculated for all patients. The lesion complexity of coronary artery disease was assessed with the SYNTAX score.<bold>Results: </bold>The CHA2DS2-VASc and SYNTAX scores were significantly lower in the SR(+) group compared to the SR(-) (mean CHA2DS2-VASc, 1.36 ± 0.64 vs. 2.01 ± 0.80, p < 0.001; mean SYNTAX score, 15.51 ± 5.94 vs. 17.08 ± 8.29, p < 0.001). After the multivariate regression analysis, a lower CHA2DS2-VASc (OR = 0.288, p < 0.001), SYNTAX score (OR = 0.920, p=0.007), uric acid (OR = 0.868, p=0.005), CRP (OR = 0.939, p=0.001), BNP (OR = 0.998, p=0.004), and troponin (OR = 0.991, p=0.001) were independent predictors of SR. In-hospital mortality rates were significantly lower in the SR(+) group compared to the SR(-) (0% vs. 6.7%, p < 0.001).<bold>Conclusion: </bold>Our study demonstrated that lesion complexity and the CHA2DS2-VASc score are independently associated with spontaneous reperfusion.
- Publication
International Journal of Clinical Practice, 2022, p1
- ISSN
1368-5031
- Publication type
journal article
- DOI
10.1155/2022/8066780