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- Title
Vogt-Koyanagi-Harada Disease Presenting as a Schizophrenia Spectrum Disorder: A Case Report.
- Authors
Kheradmand, Ali; Safarzadeh, Hannaneh
- Abstract
Introduction: Numerous autoimmune disorders accompany with psychosis. The Vogt-Koyanagi-Harada (VKH) disease is an autoimmune disease with no reports about its concomitance with psychosis so far. Case Presentation:We report the co-occurrence of schizophrenic spectrum diseases withVKHfor the first time. They havecommon manifestations such as aggression, agitation, and self-talking, subsiding after chemotherapy. Workup evaluation was performed by computed tomography (CT) scan, magnetic resonance imaging (MRI), electroencephalography (EEG), lumbar puncture (LP) study, IQ test, lab tests for hepatitis and other infections, and retinal angiography and sonography. The patient underwent corticosteroid therapy, immunosuppressive therapy, risperidone, propranolol, and trihexyphenidyl. Conclusions: Our results showed the significant role of autoimmunity in the genesis of psychosis. On the other hand, unusual manifestations and slow response to treatment in these patients show that autoimmune disorders with psychosis may worsen the prognosis of psychosis.
- Subjects
SCHIZOPHRENIA; MAGNETIC resonance imaging; AUTOIMMUNE diseases; INTELLIGENCE tests; COMPUTED tomography; LUMBAR puncture
- Publication
Iranian Journal of Psychiatry & Behavioral Sciences / Progress in Psychiatry & Behavioral Sciences, 2022, Vol 16, Issue 4, p1
- ISSN
1735-8639
- Publication type
Case Study
- DOI
10.5812/ijpbs-100423