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Age-Related Alterations in Gait Function in Freely Moving Male C57BL/6 Mice: Translational Relevance of Decreased Cadence and Increased Gait Variability.
- Published in:
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2019, v. 74, n. 9, p. 1417, doi. 10.1093/gerona/gly242
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- Publication type:
- Article
IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging.
- Published in:
- 2019
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- Publication type:
- journal article
Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline.
- Published in:
- 2019
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- Publication type:
- journal article
Age-Related Alterations in Gait Function in Freely Moving Male C57BL/6 Mice: Translational Relevance of Decreased Cadence and Increased Gait Variability.
- Published in:
- 2018
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- Publication type:
- journal article
Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype.
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- 2018
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- Publication type:
- journal article
Aging Exacerbates Pressure-Induced Mitochondrial Oxidative Stress in Mouse Cerebral Arteries.
- Published in:
- 2015
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- Publication type:
- journal article
Age-Related Decline of Autocrine Pituitary Adenylate Cyclase-Activating Polypeptide Impairs Angiogenic Capacity of Rat Cerebromicrovascular Endothelial Cells.
- Published in:
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2015, v. 70, n. 6, p. 665, doi. 10.1093/gerona/glu116
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- Publication type:
- Article
Aging Exacerbates Obesity-induced Cerebromicrovascular Rarefaction, Neurovascular Uncoupling, and Cognitive Decline in Mice.
- Published in:
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2014, v. 69, n. 11, p. 1339, doi. 10.1093/gerona/glu080
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- Publication type:
- Article
Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-00188-8
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- Publication type:
- Article
Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging.
- Published in:
- Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.788296
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- Publication type:
- Article
Neurovascular coupling, functional connectivity, and cerebrovascular endothelial extracellular vesicles as biomarkers of mild cognitive impairment.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 8, p. 5590, doi. 10.1002/alz.14072
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- Publication type:
- Article
Dimension‐based quantification of aging‐associated cerebral microvasculature determined by optical coherence tomography and two‐photon microscopy.
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- Journal of Biophotonics, 2024, v. 17, n. 3, p. 1, doi. 10.1002/jbio.202300409
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- Publication type:
- Article
Vascular mechanisms leading to progression of mild cognitive impairment to dementia after COVID-19: Protocol and methodology of a prospective longitudinal observational study.
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- PLoS ONE, 2023, v. 18, n. 8, p. 1, doi. 10.1371/journal.pone.0289508
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- Publication type:
- Article
Age‐related alterations in the cerebrovasculature affect neurovascular coupling and BOLD fMRI responses: Insights from animal models of aging.
- Published in:
- Psychophysiology, 2021, v. 58, n. 7, p. 1, doi. 10.1111/psyp.13718
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- Publication type:
- Article
Sleep deprivation alters task‐related changes in functional connectivity of the frontal cortex: A near‐infrared spectroscopy study.
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- Brain & Behavior, 2021, v. 11, n. 8, p. 1, doi. 10.1002/brb3.2135
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- Publication type:
- Article
Role of new digital technologies and telemedicine in pulmonary rehabilitation: Smart devices in the treatment of chronic respiratory diseases.
- Published in:
- Wiener Klinische Wochenschrift, 2021, v. 133, n. 21/22, p. 1201, doi. 10.1007/s00508-021-01930-y
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- Publication type:
- Article
Editorial: Endocrine regulation of aging: impacts of humoral factors and circulating mediators.
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- Frontiers in Endocrinology, 2024, p. 1, doi. 10.3389/fendo.2024.1387435
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- Publication type:
- Article
Editorial: Hippocampal mechanisms in aging and clinical memory decline.
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- Frontiers in Aging Neuroscience, 2023, p. 01, doi. 10.3389/fnagi.2023.1204954
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- Publication type:
- Article
The role of endothelial TRP channels in age-related vascular cognitive impairment and dementia.
- Published in:
- Frontiers in Aging Neuroscience, 2023, v. 15, p. 1, doi. 10.3389/fnagi.2023.1149820
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- Publication type:
- Article
Gait variability predicts cognitive impairment in older adults with subclinical cerebral small vessel disease.
- Published in:
- Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.1052451
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- Publication type:
- Article
Editorial: New developments in understanding brain and cerebromicrovascular aging: Toward prevention of vascular cognitive impairment and Alzheimer's disease.
- Published in:
- Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.1020271
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- Publication type:
- Article
Increased cognitive workload evokes greater neurovascular coupling responses in healthy young adults.
- Published in:
- PLoS ONE, 2021, v. 16, n. 5, p. 1, doi. 10.1371/journal.pone.0250043
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- Publication type:
- Article
Pharmacologically-induced neurovascular uncoupling is associated with cognitive impairment in mice.
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- Journal of Cerebral Blood Flow & Metabolism, 2015, v. 35, n. 11, p. 1871, doi. 10.1038/jcbfm.2015.162
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- Publication type:
- Article
Aging impairs myogenic adaptation to pulsatile pressure in mouse cerebral arteries.
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- Journal of Cerebral Blood Flow & Metabolism, 2015, v. 35, n. 4, p. 527, doi. 10.1038/jcbfm.2014.256
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- Publication type:
- Article
IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice.
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- Journal of Cerebral Blood Flow & Metabolism, 2014, v. 34, n. 12, p. 1887, doi. 10.1038/jcbfm.2014.156
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- Publication type:
- Article
Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension.
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- Journal of Cerebral Blood Flow & Metabolism, 2013, v. 33, n. 11, p. 1732, doi. 10.1038/jcbfm.2013.143
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- Publication type:
- Article
Linking peripheral atherosclerosis to blood–brain barrier disruption: elucidating its role as a manifestation of cerebral small vessel disease in vascular cognitive impairment.
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- GeroScience, 2024, v. 46, n. 6, p. 6511, doi. 10.1007/s11357-024-01194-0
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- Publication type:
- Article
Longitudinal detection of gait alterations associated with hypertension-induced cerebral microhemorrhages in mice: predictive role of stride length and stride time asymmetry and increased gait entropy.
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- GeroScience, 2024, v. 46, n. 5, p. 4743, doi. 10.1007/s11357-024-01210-3
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- Publication type:
- Article
Young blood-mediated cerebromicrovascular rejuvenation through heterochronic parabiosis: enhancing blood-brain barrier integrity and capillarization in the aged mouse brain.
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- GeroScience, 2024, v. 46, n. 5, p. 4415, doi. 10.1007/s11357-024-01154-8
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- Publication type:
- Article
Atherosclerotic burden and cerebral small vessel disease: exploring the link through microvascular aging and cerebral microhemorrhages.
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- GeroScience, 2024, v. 46, n. 5, p. 5103, doi. 10.1007/s11357-024-01139-7
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- Publication type:
- Article
Vascular smooth muscle cell-specific Igf1r deficiency exacerbates the development of hypertension-induced cerebral microhemorrhages and gait defects.
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- GeroScience, 2024, v. 46, n. 3, p. 3481, doi. 10.1007/s11357-024-01090-7
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- Publication type:
- Article
Irradiation-induced hair graying in mice: an experimental model to evaluate the effectiveness of interventions targeting oxidative stress, DNA damage prevention, and cellular senescence.
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- GeroScience, 2024, v. 46, n. 3, p. 3105, doi. 10.1007/s11357-023-01042-7
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- Publication type:
- Article
Whole brain irradiation–induced endothelial dysfunction in the mouse brain.
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- GeroScience, 2024, v. 46, n. 1, p. 531, doi. 10.1007/s11357-023-00990-4
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- Publication type:
- Article
Rejuvenation of cerebromicrovascular function in aged mice through heterochronic parabiosis: insights into neurovascular coupling and the impact of young blood factors.
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- GeroScience, 2024, v. 46, n. 1, p. 327, doi. 10.1007/s11357-023-01039-2
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- Publication type:
- Article
Preventing spontaneous cerebral microhemorrhages in aging mice: a novel approach targeting cellular senescence with ABT263/navitoclax.
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- GeroScience, 2024, v. 46, n. 1, p. 21, doi. 10.1007/s11357-023-01024-9
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- Article
Exposome and unhealthy aging: environmental drivers from air pollution to occupational exposures.
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- GeroScience, 2023, v. 45, n. 6, p. 3381, doi. 10.1007/s11357-023-00913-3
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- Publication type:
- Article
PCSK9: an emerging player in cardiometabolic aging and its potential as a therapeutic target and biomarker.
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- GeroScience, 2024, v. 46, n. 1, p. 257, doi. 10.1007/s11357-023-01003-0
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- Publication type:
- Article
Elimination of senescent cells by treatment with Navitoclax/ABT263 reverses whole brain irradiation-induced blood-brain barrier disruption in the mouse brain.
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- GeroScience, 2023, v. 45, n. 5, p. 2983, doi. 10.1007/s11357-023-00870-x
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- Publication type:
- Article
Imaging the time course, morphology, neuronal tissue compression, and resolution of cerebral microhemorrhages in mice using intravital two-photon microscopy: insights into arteriolar, capillary, and venular origin.
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- GeroScience, 2023, v. 45, n. 5, p. 2851, doi. 10.1007/s11357-023-00839-w
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- Publication type:
- Article
Measurements of cerebral microvascular blood flow, oxygenation, and morphology in a mouse model of whole-brain irradiation-induced cognitive impairment by two-photon microscopy and optical coherence tomography: evidence for microvascular injury in the cerebral white matter
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- GeroScience, 2023, v. 45, n. 3, p. 1491, doi. 10.1007/s11357-023-00735-3
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- Publication type:
- Article
Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain.
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- GeroScience, 2022, v. 44, n. 2, p. 661, doi. 10.1007/s11357-022-00521-7
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- Publication type:
- Article
Old blood from heterochronic parabionts accelerates vascular aging in young mice: transcriptomic signature of pathologic smooth muscle remodeling.
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- GeroScience, 2022, v. 44, n. 2, p. 953, doi. 10.1007/s11357-022-00519-1
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- Article
Cerebral venous congestion exacerbates cerebral microhemorrhages in mice.
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- GeroScience, 2022, v. 44, n. 2, p. 805, doi. 10.1007/s11357-021-00504-0
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- Publication type:
- Article
Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice.
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- GeroScience, 2021, v. 43, n. 5, p. 2611, doi. 10.1007/s11357-021-00402-5
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- Publication type:
- Article
Animal reservoirs of SARS-CoV-2: calculable COVID-19 risk for older adults from animal to human transmission.
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- GeroScience, 2021, v. 43, n. 5, p. 2305, doi. 10.1007/s11357-021-00444-9
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- Publication type:
- Article
Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype.
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- GeroScience, 2021, v. 43, n. 5, p. 2387, doi. 10.1007/s11357-021-00405-2
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- Publication type:
- Article
Treatment with the BCL-2/BCL-xL inhibitor senolytic drug ABT263/Navitoclax improves functional hyperemia in aged mice.
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- GeroScience, 2021, v. 43, n. 5, p. 2427, doi. 10.1007/s11357-021-00440-z
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- Article
Early manifestation of gait alterations in the Tg2576 mouse model of Alzheimer's disease.
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- GeroScience, 2021, v. 43, n. 4, p. 1947, doi. 10.1007/s11357-021-00401-6
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- Publication type:
- Article
IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging.
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- GeroScience, 2021, v. 43, n. 2, p. 901, doi. 10.1007/s11357-021-00350-0
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- Publication type:
- Article
Whole brain irradiation in mice causes long-term impairment in astrocytic calcium signaling but preserves astrocyte-astrocyte coupling.
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- GeroScience, 2021, v. 43, n. 1, p. 197, doi. 10.1007/s11357-020-00289-8
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- Publication type:
- Article