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- Title
Effects of Some Food Components on Non-Alcoholic Fatty Liver Disease Severity: Results from a Cross-Sectional Study.
- Authors
Mirizzi, Antonella; Franco, Isabella; Leone, Carla Maria; Bonfiglio, Caterina; Cozzolongo, Raffaele; Notarnicola, Maria; Giannuzzi, Vito; Tutino, Valeria; De Nunzio, Valentina; Bruno, Irene; Buongiorno, Claudia; Campanella, Angelo; Deflorio, Valentina; Pascale, Annamaria; Procino, Filippo; Sorino, Paolo; Osella, Alberto Rubén
- Abstract
Background: The high prevalence of non-alcoholic fatty liver disease (NAFLD) observed in Western countries is due to the concurrent epidemics of overweight/obesity and associated metabolic complications, both recognized risk factors. A Western dietary pattern has been associated with weight gain and obesity, and more recently with NAFLD. Methods: This is a baseline cross-sectional analysis of 136 subjects (79 males) enrolled consecutively in the NUTRIATT (NUTRItion and Ac-TiviTy) study. Study subjects had moderate or severe NAFLD diagnosed by using Fibroscan-CAP. Food Frequency Questionnaire was used to obtain information about food intake. Statistical analysis included descriptive statistics and a multivariable logistic regression model. Results: The mean age was 49.58 (±10.18) with a mean BMI of 33.41 (±4.74). A significant inverse relationship was revealed between winter ice-cream intake and NAFLD severity (O.R. 0.65, 95% C.I. 0.95–0.99); chickpeas intake and NAFLD severity (O.R. 0.57, 95% C.I. 0.34–0.97), and not industrial aged-cheeses type (O.R. 0.85, 95% C.I. 0.74–0.98). A statistically significant positive association also emerged between rabbit meat (O.R. 1.23, 95% C.I. 1.01–1.49), industrial type aged cheeses (O.R. 1.17, 95% C.I. 1.01–1.35), milk-based desserts (no winter ice cream) (O.R. 1.11, 95% C.I. 1.01–1.21), fats (O.R. 1.12, 95% C.I. 1.01–1.25), and NAFLD severity. Conclusion: The fresh foods from non-intensive farming and high legume intake that characterize the Mediterranean diet would seem to be beneficial for patients with NAFLD.
- Subjects
CHEESE; CONFIDENCE intervals; DAIRY products; FATTY liver; FAT content of food; INGESTION; MEAT; OBESITY; QUESTIONNAIRES; LOGISTIC regression analysis; BODY mass index; CROSS-sectional method; SEVERITY of illness index; DESCRIPTIVE statistics; MEDITERRANEAN diet; ODDS ratio
- Publication
Nutrients, 2019, Vol 11, Issue 11, p2744
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu11112744