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Prodrugs of γ‐Alkyl‐Modified Nucleoside Triphosphates: Improved Inhibition of HIV Reverse Transcriptase.
- Published in:
- Angewandte Chemie, 2020, v. 132, n. 49, p. 22247, doi. 10.1002/ange.202003073
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- Publication type:
- Article
Membrane-permeable Triphosphate Prodrugs of Nucleoside Analogues.
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- Angewandte Chemie, 2016, v. 128, n. 17, p. 5341, doi. 10.1002/ange.201511808
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- Publication type:
- Article
Synthesis and biological evaluation of carbon-11-labeled acyclic and furo[2,3-d]pyrimidine derivatives of bicyclic nucleoside analogues (BCNAs) for structure-brain uptake relationship study of BCNA tracers.
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- Journal of Labelled Compounds & Radiopharmaceuticals, 2008, v. 51, n. 3, p. 159, doi. 10.1002/jlcr.1494
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- Publication type:
- Article
Synthesis and biological evaluation of a lipophilic, fluorine-18-labeled 5-ethynyl-2′-deoxyuridine derivative.
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- Journal of Labelled Compounds & Radiopharmaceuticals, 2007, v. 50, n. 7, p. 649, doi. 10.1002/jlcr.1312
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- Publication type:
- Article
Solid state properties of pure UC-781 and solid dispersions with polyvinylpyrrolidone (PVP K30).
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- Journal of Pharmacy & Pharmacology, 2001, v. 53, n. 8, p. 1109, doi. 10.1211/0022357011776496
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- Publication type:
- Article
In vitro synergistic activity against CCR5-tropic HIV-1 with combinations of potential candidate microbicide molecules HHA, KRV2110 and enfuvirtide (T20).
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- Journal of Antimicrobial Chemotherapy (JAC), 2009, v. 64, n. 6, p. 1192, doi. 10.1093/jac/dkp380
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- Publication type:
- Article
FV100 as a new approach for the possible treatment of varicella-zoster virus infection.
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- Journal of Antimicrobial Chemotherapy (JAC), 2009, v. 64, n. 4, p. 671, doi. 10.1093/jac/dkp294
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- Publication type:
- Article
Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus.
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- Journal of Antimicrobial Chemotherapy (JAC), 2007, v. 60, n. 6, p. 1316, doi. 10.1093/jac/dkm376
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- Publication type:
- Article
Pronounced in vitro and in vivo antiretroviral activity of 5-substituted 2,4-diamino-6-[2-(phosphonomethoxy)ethoxy] pyrimidines.
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- Journal of Antimicrobial Chemotherapy (JAC), 2007, v. 59, n. 1, p. 80
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- Publication type:
- Article
Pyridine N-oxide derivatives are inhibitory to the human SARS and feline infectious peritonitis coronavirus in cell culture.
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- Journal of Antimicrobial Chemotherapy (JAC), 2006, v. 57, n. 3, p. 472, doi. 10.1093/jac/dki481
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- Publication type:
- Article
Cell-dependent interference of a series of new 6-aminoquinolone derivatives with viral (HIV/CMV) transactivation.
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- Journal of Antimicrobial Chemotherapy (JAC), 2005, v. 56, n. 5, p. 847, doi. 10.1093/jac/dki328
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- Publication type:
- Article
Limited development and progression of resistance of HIV-1 to the nucleoside analogue reverse transcriptase inhibitor lamivudine in human primary macrophages.
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- Journal of Antimicrobial Chemotherapy (JAC), 2005, v. 55, n. 6, p. 872, doi. 10.1093/jac/dki104
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- Publication type:
- Article
Bicyclic pyrimidine nucleoside analogues (BCNAs) as highly selective and potent inhibitors of varicella-zoster virus replication.
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- 2002
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- Publication type:
- journal article
Viruses as key regulators of angiogenesis.
- Published in:
- Reviews in Medical Virology, 2011, v. 21, n. 3, p. 181, doi. 10.1002/rmv.688
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- Publication type:
- Article
Membrane-permeable Triphosphate Prodrugs of Nucleoside Analogues.
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- Angewandte Chemie International Edition, 2016, v. 55, n. 17, p. 5255, doi. 10.1002/anie.201511808
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- Publication type:
- Article
Synthesis and Anti- HIV Activity of 4-(Naphthalen-1-yl)-1,2,5-thiadiazol-3-hydroxyl Derivatives.
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- Chemical Biology & Drug Design, 2014, v. 84, n. 4, p. 420, doi. 10.1111/cbdd.12328
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- Publication type:
- Article
Design, Synthesis, and Biological Evaluation of Novel 3,5-Disubstituted-1,2,6-Thiadiazine-1,1-Dione Derivatives as HIV-1 NNRTIs.
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- Chemical Biology & Drug Design, 2013, v. 82, n. 4, p. 384, doi. 10.1111/cbdd.12160
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- Publication type:
- Article
Cytostatic and Antiviral Activity Evaluations of Hydroxamic Derivatives of Some Non-steroidal Anti-inflammatory Drugs.
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- Chemical Biology & Drug Design, 2009, v. 73, n. 3, p. 328, doi. 10.1111/j.1747-0285.2009.00774.x
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- Publication type:
- Article
Enantiocontrolled Preparation of ϒ-Substituted Cyclohexenones: Synthesis and Kinase Activity Assays of Cyclopropyl-Fused Cyclohexane Nucleosides.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 17, p. 9704, doi. 10.3390/ijms23179704
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- Publication type:
- Article
Structure of vaccinia virus thymidine kinase in complex with dTTP: insights for drug design.
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- BMC Structural Biology, 2006, v. 6, p. 22, doi. 10.1186/1472-6807-6-22
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- Publication type:
- Article
3′-(1,2,3-Triazol-1-yl)-2′,3′-dideoxythymidine and 3′-(1,2,3-triazol-1-yl)-2′,3′-dideoxyuridine.
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- Journal of Heterocyclic Chemistry, 1989, v. 26, n. 6, p. 1635, doi. 10.1002/jhet.5570260624
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- Publication type:
- Article
Potent and Selective Anti-HIV Activity of 5-Chloro-Substituted Derivatives of 3′-Azido-2′,3′-Dideoxycytidine, 3′-Fluoro-2′,3′-Dideoxycytidine, and 2′,3′-Didehydro-2′,3′-Dideoxycytidine.
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- Annals of the New York Academy of Sciences, 1991, v. 616, n. 1, p. 480, doi. 10.1111/j.1749-6632.1990.tb17870.x
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- Publication type:
- Article
Antiviral Activity of Heparin and Dextran Sulfate against Human Immunodeficiency Virus (HIV) in Vitro.
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- Annals of the New York Academy of Sciences, 1989, v. 556, n. 1, p. 419, doi. 10.1111/j.1749-6632.1989.tb22523.x
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- Publication type:
- Article
Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues.
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- Biochemical Journal, 2012, v. 445, n. 1, p. 113, doi. 10.1042/BJ20112225
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- Publication type:
- Article
Anti-retrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine (pmea) in vivo increases when it is less frequently administered.
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- International Journal of Cancer, 1990, v. 46, n. 2, p. 337, doi. 10.1002/ijc.2910460233
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- Publication type:
- Article
Inhibitory effects of 9-(2-Phosphonylmethoxyethyl)adenine and 3′-azido-2′,3′-dideoxythymidine on tumor development in mice inoculated intracerebrally with moloney murine sarcoma virus.
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- International Journal of Cancer, 1990, v. 45, n. 3, p. 486, doi. 10.1002/ijc.2910450319
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- Publication type:
- Article
Comparative inhibitory effects of suramin and other selected compounds on the infectivity and replication of human T-cell lymphotropic virus (HTLV-III)/lymphadenopathy-associated virus (LAV).
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- International Journal of Cancer, 1986, v. 37, n. 3, p. 451, doi. 10.1002/ijc.2910370318
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- Publication type:
- Article
Synthesis and Antiviral Activity of Water‐Soluble Polycarboxylic Derivatives of [60]Fullerene Loaded with 3,4‐Dichlorophenyl Units.
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- Chemistry & Biodiversity, 2018, v. 15, n. 11, p. N.PAG, doi. 10.1002/cbdv.201800293
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- Publication type:
- Article
Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors. Part 13.
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- Chemistry & Biodiversity, 2009, v. 6, n. 4, p. 561, doi. 10.1002/cbdv.200800163
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- Publication type:
- Article
Non-Nucleoside HIV-1 Reverse-Transcriptase Inhibitors. Part 10.
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- Chemistry & Biodiversity, 2008, v. 5, n. 1, p. 168, doi. 10.1002/cbdv.200890008
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- Publication type:
- Article
Exposure of Trypanosoma brucei to an N-acetylglucosamine-Binding Lectin Induces VSG Switching and Glycosylation Defects Resulting in Reduced Infectivity.
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- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 3, p. 1, doi. 10.1371/journal.pntd.0003612
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- Publication type:
- Article
Exposure of Trypanosoma brucei to an N-acetylglucosamine-Binding Lectin Induces VSG Switching and Glycosylation Defects Resulting in Reduced Infectivity.
- Published in:
- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 3, p. 1, doi. 10.1371/journal.pntd.0003612
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- Publication type:
- Article
γ‐Non‐Symmetrically Dimasked TriPPPro Prodrugs as Potential Antiviral Agents against HIV.
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- ChemMedChem, 2021, v. 16, n. 3, p. 499, doi. 10.1002/cmdc.202000712
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- Publication type:
- Article
Symmetrical Diamidates as a Class of Phosphate Prodrugs to Deliver the 5′‐Monophosphate Forms of Anticancer Nucleoside Analogues.
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- ChemMedChem, 2018, v. 13, n. 21, p. 2305, doi. 10.1002/cmdc.201800504
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- Publication type:
- Article
Antiviral Activity of the Human Immunodeficiency Virus Type 1-Specific Nonnucleoside Reverse Transcriptase Inhibitor HBY 097 Alone and in Combination with Zidovudine in a Phase II Study.
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- Journal of Infectious Diseases, 1999, v. 179, n. 3, p. 709
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- Publication type:
- Article
Multiple Drug Resistance to Nucleoside Analogues and Nonnucleoside Reverse Transcriptase Inhibitors in an Efficiently Replicating Human Immunodeficiency Virus Type 1 Patient Strain.
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- Journal of Infectious Diseases, 1996, v. 174, n. 5, p. 962, doi. 10.1093/infdis/174.5.962
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- Publication type:
- Article
Novel Lipophilic Hydroxyurea Derivatives: Synthesis, Cytostatic and Antiviral Activity Evaluations.
- Published in:
- Chemical Biology & Drug Design, 2008, v. 71, n. 6, p. 546, doi. 10.1111/j.1747-0285.2008.00660.x
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- Publication type:
- Article
Substrate specificity of vaccinia virus thymidylate kinase.
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- FEBS Journal, 2005, v. 272, n. 24, p. 6254, doi. 10.1111/j.1742-4658.2005.05006.x
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- Publication type:
- Article
Altered deoxyribonucleotide pools in T-lymphoblastoid cells expressing the multisubstrate nucleoside kinase of Drosophila melanogaster.
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- FEBS Journal, 2005, v. 272, n. 15, p. 3918, doi. 10.1111/j.1742-4658.2005.04808.x
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- Publication type:
- Article
Synthesis of 5-Amino-3,3-dimethyl-7-phenyl-3 H-[1,2]oxathiolo[4,3- b]pyridine-6-carbonitrile 1,1-Dioxides.
- Published in:
- Journal of Heterocyclic Chemistry, 2014, v. 51, n. 5, p. 1452, doi. 10.1002/jhet.1678
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- Publication type:
- Article
Cyclopentene carbocyclic nucleosides related to the antitumor nucleoside clitocine and their conversion to 8-Aza-neplanocin analogues. Synthesis and antiviral activity.
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- Journal of Heterocyclic Chemistry, 1993, v. 30, n. 5, p. 1393, doi. 10.1002/jhet.5570300536
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- Publication type:
- Article
Synthesis of 2-carbamoylmethyl-6-β-D-ribofuranosylpyridine with the aid of a Pd(0)-catalyzed reaction.
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- Journal of Heterocyclic Chemistry, 1993, v. 30, n. 5, p. 1245, doi. 10.1002/jhet.5570300513
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- Publication type:
- Article
High mannose-specific lectin Msl mediates key interactions of the vaginal Lactobacillus plantarum isolate CMPG5300.
- Published in:
- Scientific Reports, 2016, p. 37339, doi. 10.1038/srep37339
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- Publication type:
- Article
Role of MRP4 and MRP5 in biology and chemotherapy.
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- AAPS Journal, 2002, v. 4, n. 3, p. 22, doi. 10.1208/ps040314
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- Publication type:
- Article
Several N-Glycans on the HIV Envelope Glycoprotein gp120 Preferentially Locate Near Disulphide Bridges and Are Required for Efficient Infectivity and Virus Transmission.
- Published in:
- PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0130621
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- Publication type:
- Article
Deletion of the Highly Conserved <i>N</i>-Glycan at Asn260 of HIV-1 gp120 Affects Folding and Lysosomal Degradation of gp120, and Results in Loss of Viral Infectivity.
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- PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0101181
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- Publication type:
- Article
Role of the Carbohydrate-Binding Sites of Griffithsin in the Prevention of DC-SIGN-Mediated Capture and Transmission of HIV-1
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- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064132
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- Publication type:
- Article
The Lantibiotic Peptide Labyrinthopeptin A1 Demonstrates Broad Anti-HIV and Anti-HSV Activity with Potential for Microbicidal Applications
- Published in:
- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064010
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- Publication type:
- Article
Pan-Pathway Based Interaction Profiling of FDAApproved Nucleoside and Nucleobase Analogs with Enzymes of the Human Nucleotide Metabolism.
- Published in:
- PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037724
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- Publication type:
- Article
DC-SIGN Increases the Affinity of HIV-1 Envelope Glycoprotein Interaction with CD4.
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- PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0028307
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- Publication type:
- Article