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- Title
What is your diagnosis? Muculent pleural effusion from a dog.
- Authors
Riegel, Casey M.; Stockham, Steven L.; Patton, Kristin M.; Thomas, Casey L.
- Abstract
Pleural effusion was examined from a 5-year-old, female Brittany Spaniel with a 7-day history of dyspnea, anorexia, and diarrhea. The fluid was yellow, cloudy, and slightly gelatinous, and had a total protein concentration of 2.8 g/dL, a total nucleated cell concentration of 1.1 × 103/μL, and a triglyceride concentration of 177 mg/dL. A cytocentrifuged preparation contained a mixed inflammatory cell population with a predominance of small lymphocytes and abundant mucinous material in the background. The dog died 3 days later and a mass was found within the lumen and wall of the right auricle of the heart at necropsy. Histopathologic sections of the mass contained a population of anaplastic spindle cells diffusely suspended in a pale basophilic matrix, consistent with myxosarcoma. The cells were positive for vimentin and negative for cytokeratin, desmin, and von Willebrand factor VIII-related antigen. A myxoid matrix was confirmed by positive staining with Alcian blue. Myxosarcoma is a rare cardiac tumor in dogs that should be considered, along with mucus-producing carcinomas and bile, as a cause of muculent effusion.
- Subjects
PLEURAL effusions; BRITTANY spaniel; DYSPNEA; APPETITE loss; DIARRHEA; TRIGLYCERIDES
- Publication
Veterinary Clinical Pathology, 2008, Vol 37, Issue 3, p353
- ISSN
0275-6382
- Publication type
Article
- DOI
10.1111/j.1939-165X.2008.00043.x