We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Animal models of psoriasis: a brief update.
- Authors
Nestle, F. O.; Nickoloff, B. J.
- Abstract
Major obstacles to improve our understanding of psoriasis pathogenesis and development of new therapies are in large part due to the absence of accepted and disease-relevant in-vivo models. Recent progress in the area of psoriasis disease models include the use of humanized xenotransplantation models and genetically altered mice reflecting psoriasiform pathology. These models provide exciting new insights into disease pathogenesis and will hopefully enable improved pathogenesis-based drug approaches.
- Subjects
ANIMAL models in research; PSORIASIS; GENE mapping; SKIN inflammation; KERATINOCYTES; ANIMAL models of organ transplants; DRUG development
- Publication
Journal of the European Academy of Dermatology & Venereology, 2006, Vol 20, p24
- ISSN
0926-9959
- Publication type
Article
- DOI
10.1111/j.1468-3083.2006.01769.x