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- Title
Reversible Posterior Leukoencephalopathy Syndrome in a Patient with Dermatomyositis.
- Authors
Yu-You Zhu; Juan Wang; Yuan-Bo Wu; Yan Ma
- Abstract
Background: Dermatomyositis (DM) is an auto-immune disorder of the central nervous system that is characterized by inflammation of the muscles and the skin. Reversible posterior leukoencephalopathy syndrome (RPLS) is characterized by headache, confusion, seizures and visual loss and has been associated with other auto-immune diseases. In this study, we describe for the first time the association of RPLS with DM. Case Report: A 34 year old male patient with a diagnosis of DM for 3 years was treated with oral corticosteroids and other drugs intermittently. Patient developed sudden dizziness, severe headache, nausea, vomiting, irritability, and loss of consciousness followed by generalized tonic clonic seizures and was diagnosed with RPLS following a MRI of the brain. Treatment: The patient received oral nifidepine, intra-venous mannitol and phenobarbital sodium. Patient recovered fully three days after admission and a follow up MRI performed one month after discharge revealed almost completely resolved bilateral lesions in the brain. Conclusion: RPLS could be associated with dematomyositis and a timely MRI could aid in the diagnosis as well as its treatment.
- Subjects
NIFEDIPINE; MANNITOL; POSTERIOR leukoencephalopathy syndrome; PHENOBARBITAL; DERMATOMYOSITIS; MAGNETIC resonance imaging; DIAGNOSIS; THERAPEUTICS
- Publication
International Medical Journal, 2015, Vol 22, Issue 1, p53
- ISSN
1341-2051
- Publication type
Article