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- Title
A Piece in the Puzzle of Personalized Medicine.
- Authors
Kroemer, H. K.; Schwabedissen, H. E. Meyer zu
- Abstract
Predicting individual drug response based on inherited factors remains a major challenge. Some examples of significant contributions of single genetic variants to overall therapeutic success of drugs in complex diseases are currently emerging. For most compounds, however, multiple genetic and nongenetic factors will modify drug action. Comprehensive integration of these factors will determine the role of pharmacogenomics for personalized medicine.
- Subjects
DOSE-effect relationship in pharmacology; THERAPEUTIC equivalency in drugs; IMMUNE complex diseases; MEDICATION abuse; PHARMACOGENOMICS
- Publication
Clinical Pharmacology & Therapeutics, 2010, Vol 87, Issue 1, p19
- ISSN
0009-9236
- Publication type
Article
- DOI
10.1038/clpt.2009.219