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- Title
The Challenges of Using and Measuring Thiamine in Critical Care.
- Authors
Mumin, Muhammad Ashraful; McKenzie, Cathrine Anne; Spronk, Peter Erwin
- Abstract
The article informs about the outcomes of a randomized clinical trial on intravenous thiamine for renal protection in septic shock, noting the absence of statistically significant effects on primary and secondary endpoints. Topic include It raises concerns regarding the dosing and pharmacokinetics of intravenous thiamine in septic shock, the potential impact on delirium incidence, and the importance of measuring whole-blood thiamine levels for a comprehensive understanding of its effects.
- Subjects
VITAMIN B1; CRITICAL care medicine; THIAMIN pyrophosphate; WERNICKE'S encephalopathy
- Publication
American Journal of Respiratory & Critical Care Medicine, 2024, Vol 209, Issue 5, p606
- ISSN
1073-449X
- Publication type
Article
- DOI
10.1164/rccm.202309-1641LE