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- Title
Glycopolyoxazoline-lectin interactions. Effects of ligand structure on clustering kinetics.
- Authors
DIEHL, CHRISTINA; SCHLAAD, HELMUT
- Abstract
Turbidimetric measurements were used to examine the clustering of concanavalin A (Con A) with glucosylated polyoxazolines. For homopolymers, and also block copolymers, precipitation of Con A occured faster with longer glucoslyated chains and higher valency of the ligand. For statistical copolymers, the same trend was observed for increasing spacing between glucose residues or decreasing epitope density. Also the nature of the non-binding side chains appeared to have impact on the clustering kinetics.
- Subjects
OXAZOLINE; LECTINS; MOLECULAR structure of ligands; TURBIDIMETRY; CONCANAVALIN A; CLUSTERING of particles; CHEMICAL kinetics; BLOCK copolymers
- Publication
Polimery, 2013, Vol 58, Issue 9, p650
- ISSN
0032-2725
- Publication type
Article
- DOI
10.14314/polimery.2013.650