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- Title
ANCA-associated vasculitis with dual ANCA positivity in coexistence with mixed connective tissue disease.
- Authors
Murakami, Masanori; Shimane, Kenichi; Takahashi, Hiroshi; Tomiyama, Junji; Nagashima, Masakazu
- Abstract
We here report a rare case of dual antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in a 38-year-old Japanese woman previously diagnosed with mixed connective tissue disease. The patient was found to be positive for myeloperoxidase- and proteinase 3-ANCA, and was diagnosed with AAV following admission to hospital with fervescence, polyarthralgia, purpura, and asymmetric numbness of the extremities. Examination of her genetic background revealed that she carried HLA-DR9, which confers risk of both diseases in Japanese populations.
- Subjects
VASCULITIS treatment; CYTOPLASM; MYELOPEROXIDASE; NEUTROPHILS; IMMUNOGLOBULINS; MIXED connective tissue disease
- Publication
Modern Rheumatology, 2013, Vol 23, Issue 1, p156
- ISSN
1439-7595
- Publication type
Article
- DOI
10.3109/s10165-012-0619-8