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- Title
STUDY ON THE PROTECTIVE EFFECTS OF ALLICIN (THIOSULFANATE) AGAINST TESTICULAR TOXICITY OF OXIDANT AGENT (ZINC OXIDE) IN MALE RATS.
- Authors
Habeeb, Sanna Abadi; Bashboosh, Nawras Noori; Samiermhana, Israa
- Abstract
The aim of this study is to investigate the protective effect of the allicin (thiosulfanate) in the histological alterations of testes induced by oxidant agentzinc oxide (ZnO). The first group of the rats was negative control group. The second treatment groups were treated 5oppm of allicin, the third by ZnO and the fourth group treated with allicin +ZnO. All doses were given orally by gastric intubation with allicinwhile ZnO by injection, the experiment continued daily for 30 days. Due to experimental intoxication with ZnO, the microscopic examination for the testes in rats revealed numerous histological lesions in the seminiferous tubules and the interstitial tissue. In contrast, the histopathologic changes of testes were partially reversed by treatment with allicin extraction and the testes appeared with nearly normal structure. It may be concluded that allicin revealed protective effect against the reproductive toxicity of ZnO.
- Publication
Biochemical & Cellular Archives, 2018, Vol 18, Issue 2, p1947
- ISSN
0972-5075
- Publication type
Article