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Human seasonal coronavirus neutralization and COVID‐19 severity.
Published in:
Journal of Medical Virology, 2022, v. 94, n. 10, p. 4820, doi. 10.1002/jmv.27937
By:
- Wells, David A.;
- Cantoni, Diego;
- Mayora‐Neto, Martin;
- Genova, Cecilia Di;
- Sampson, Alexander;
- Ferrari, Matteo;
- Carnell, George;
- Nadesalingam, Angalee;
- Smith, Peter;
- Chan, Andrew;
- Raddi, Gianmarco;
- Castillo‐Olivares, Javier;
- Baxendale, Helen;
- Temperton, Nigel;
- Heeney, Jonathan L.
Publication type:
Article
Influenza A (N1-N9) and Influenza B (B/Victoria and B/Yamagata) Neuraminidase Pseudotypes as Tools for Pandemic Preparedness and Improved Influenza Vaccine Design.
Published in:
Vaccines, 2022, v. 10, n. 9, p. 1520, doi. 10.3390/vaccines10091520
By:
- da Costa, Kelly A. S.;
- Del Rosario, Joanne Marie M.;
- Ferrari, Matteo;
- Vishwanath, Sneha;
- Asbach, Benedikt;
- Kinsley, Rebecca;
- Wagner, Ralf;
- Heeney, Jonathan L.;
- Carnell, George W.;
- Temperton, Nigel J.
Publication type:
Article
Stepwise Conformational Stabilization of a HIV-1 Clade C Consensus Envelope Trimer Immunogen Impacts the Profile of Vaccine-Induced Antibody Responses.
Published in:
Vaccines, 2021, v. 9, n. 7, p. 750, doi. 10.3390/vaccines9070750
By:
- Hauser, Alexandra;
- Carnell, George;
- Held, Kathrin;
- Sulbaran, Guidenn;
- Tischbierek, Nadine;
- Rogers, Lisa;
- Pollakis, Georgios;
- Tonks, Paul;
- Hoelscher, Michael;
- Ding, Song;
- Sanders, Rogier W.;
- Geldmacher, Christof;
- Sattentau, Quentin;
- Weissenhorn, Winfried;
- Heeney, Jonathan L.;
- Peterhoff, David;
- Wagner, Ralf
Publication type:
Article
Exploiting Pan Influenza A and Pan Influenza B Pseudotype Libraries for Efficient Vaccine Antigen Selection.
Published in:
Vaccines, 2021, v. 9, n. 7, p. 741, doi. 10.3390/vaccines9070741
By:
- Del Rosario, Joanne Marie M.;
- da Costa, Kelly A. S.;
- Asbach, Benedikt;
- Ferrara, Francesca;
- Ferrari, Matteo;
- Wells, David A.;
- Mann, Gurdip Singh;
- Ameh, Veronica O.;
- Sabeta, Claude T.;
- Banyard, Ashley C.;
- Kinsley, Rebecca;
- Scott, Simon D.;
- Wagner, Ralf;
- Heeney, Jonathan L.;
- Carnell, George W.;
- Temperton, Nigel J.
Publication type:
Article
Correlation of Influenza B Haemagglutination Inhibiton, Single-Radial Haemolysis and Pseudotype-Based Microneutralisation Assays for Immunogenicity Testing of Seasonal Vaccines.
Published in:
Vaccines, 2021, v. 9, n. 2, p. 100, doi. 10.3390/vaccines9020100
By:
- Carnell, George W.;
- Trombetta, Claudia M.;
- Ferrara, Francesca;
- Montomoli, Emanuele;
- Temperton, Nigel J.;
- Plant, Ewan;
- Xie, Hang
Publication type:
Article
Neutralisation Hierarchy of SARS-CoV-2 Variants of Concern Using Standardised, Quantitative Neutralisation Assays Reveals a Correlation With Disease Severity; Towards Deciphering Protective Antibody Thresholds.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.773982
By:
- Cantoni, Diego;
- Mayora-Neto, Martin;
- Nadesalingam, Angalee;
- Wells, David A.;
- Carnell, George W.;
- Ohlendorf, Luis;
- Ferrari, Matteo;
- Palmer, Phil;
- Chan, Andrew C.Y.;
- Smith, Peter;
- Bentley, Emma M.;
- Einhauser, Sebastian;
- Wagner, Ralf;
- Page, Mark;
- Raddi, Gianmarco;
- Baxendale, Helen;
- Castillo-Olivares, Javier;
- Heeney, Jonathan;
- Temperton, Nigel
Publication type:
Article
AutoPlate: Rapid Dose-Response Curve Analysis for Biological Assays.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2021.681636
By:
- Palmer, Phil;
- Del Rosario, Joanne Marie M.;
- da Costa, Kelly A. S.;
- Carnell, George W.;
- Huang, Chloe Q.;
- Heeney, Jonathan L.;
- Temperton, Nigel J.;
- Wells, David A.
Publication type:
Article
Analysis of Serological Biomarkers of SARS-CoV-2 Infection in Convalescent Samples From Severe, Moderate and Mild COVID-19 Cases.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.748291
By:
- Castillo-Olivares, Javier;
- Wells, David A.;
- Ferrari, Matteo;
- Chan, Andrew C. Y.;
- Smith, Peter;
- Nadesalingam, Angalee;
- Paloniemi, Minna;
- Carnell, George W.;
- Ohlendorf, Luis;
- Cantoni, Diego;
- Mayora-Neto, Martin;
- Palmer, Phil;
- Tonks, Paul;
- Temperton, Nigel J.;
- Peterhoff, David;
- Neckermann, Patrick;
- Wagner, Ralf;
- Doffinger, Rainer;
- Kempster, Sarah;
- Otter, Ashley D.
Publication type:
Article
Stalking influenza by vaccination with pre-fusion headless HA mini-stem.
Published in:
Scientific Reports, 2016, p. 22666, doi. 10.1038/srep22666
By:
- Valkenburg, Sophie A.;
- Mallajosyula, V. Vamsee Aditya;
- Li, Olive T. W.;
- Chin, Alex W. H.;
- Carnell, George;
- Temperton, Nigel;
- Varadarajan, Raghavan;
- Poon, Leo L. M.
Publication type:
Article
Cross-Protective Immune Responses Induced by Sequential Influenza Virus Infection and by Sequential Vaccination With Inactivated Influenza Vaccines.
Published in:
Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02312
By:
- Dong, Wei;
- Bhide, Yoshita;
- Sicca, Federica;
- Meijerhof, Tjarko;
- Guilfoyle, Kate;
- Engelhardt, Othmar G.;
- Boon, Louis;
- de Haan, Cornelis A. M.;
- Carnell, George;
- Temperton, Nigel;
- de Vries-Idema, Jacqueline;
- Kelvin, David;
- Huckriede, Anke
Publication type:
Article
Tetherin antagonism by SARS‐CoV‐2 ORF3a and spike protein enhances virus release.
Published in:
EMBO Reports, 2023, v. 24, n. 12, p. 1, doi. 10.15252/embr.202357224
By:
- Stewart, Hazel;
- Palmulli, Roberta;
- Johansen, Kristoffer H;
- McGovern, Naomi;
- Shehata, Ola M;
- Carnell, George W;
- Jackson, Hannah K;
- Lee, Jin S;
- Brown, Jonathan C;
- Burgoyne, Thomas;
- Heeney, Jonathan L;
- Okkenhaug, Klaus;
- Firth, Andrew E;
- Peden, Andrew A;
- Edgar, James R
Publication type:
Article
Editorial: Novel approaches to prevention, diagnosis, and treatment of bacterial and viral infections of clinical relevance.
Published in:
Frontiers in Microbiology, 2023, p. 1, doi. 10.3389/fmicb.2023.1192435
By:
- Leanse, Leon G.;
- Trombetta, Claudia Maria;
- Carnell, George W.
Publication type:
Article
Computationally designed Spike antigens induce neutralising responses against the breadth of SARS-COV-2 variants.
Published in:
NPJ Vaccines, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41541-024-00950-9
By:
- Vishwanath, Sneha;
- Carnell, George William;
- Billmeier, Martina;
- Ohlendorf, Luis;
- Neckermann, Patrick;
- Asbach, Benedikt;
- George, Charlotte;
- Sans, Maria Suau;
- Chan, Andrew;
- Olivier, Joey;
- Nadesalingam, Angalee;
- Einhauser, Sebastian;
- Temperton, Nigel;
- Cantoni, Diego;
- Grove, Joe;
- Jordan, Ingo;
- Sandig, Volker;
- Tonks, Paul;
- Geiger, Johannes;
- Dohmen, Christian
Publication type:
Article
Development of Lentiviral Vectors Pseudotyped With Influenza B Hemagglutinins: Application in Vaccine Immunogenicity, mAb Potency, and Sero-Surveillance Studies.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.661379
By:
- Ferrara, Francesca;
- Del Rosario, Joanne Marie M.;
- da Costa, Kelly A. S.;
- Kinsley, Rebecca;
- Scott, Simon;
- Fereidouni, Sasan;
- Thompson, Craig;
- Kellam, Paul;
- Gilbert, Sarah;
- Carnell, George;
- Temperton, Nigel
Publication type:
Article
Coronavirus Pseudotypes for All Circulating Human Coronaviruses for Quantification of Cross-Neutralizing Antibody Responses.
Published in:
Viruses (1999-4915), 2021, v. 13, n. 8, p. 1579, doi. 10.3390/v13081579
By:
- Sampson, Alexander Thomas;
- Heeney, Jonathan;
- Cantoni, Diego;
- Ferrari, Matteo;
- Sans, Maria Suau;
- George, Charlotte;
- Di Genova, Cecilia;
- Mayora Neto, Martin;
- Einhauser, Sebastian;
- Asbach, Benedikt;
- Wagner, Ralf;
- Baxendale, Helen;
- Temperton, Nigel;
- Carnell, George
Publication type:
Article
Nanobodies mapped to cross-reactive and divergent epitopes on A(H7N9) influenza hemagglutinin using yeast display.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-82356-4
By:
- Gaiotto, Tiziano;
- Ramage, Walter;
- Ball, Christina;
- Risley, Paul;
- Carnell, George W.;
- Temperton, Nigel;
- Engelhardt, Othmar G.;
- Hufton, Simon E.
Publication type:
Article
Cross-Reactive and Lineage-Specific Single Domain Antibodies against Influenza B Hemagglutinin.
Published in:
Antibodies (2073-4468), 2019, v. 8, n. 1, p. 14, doi. 10.3390/antib8010014
By:
- Ramage, Walter;
- Gaiotto, Tiziano;
- Ball, Christina;
- Risley, Paul;
- Carnell, George W.;
- Temperton, Nigel;
- Cheung, Chung Y.;
- Engelhardt, Othmar G.;
- Hufton, Simon E.
Publication type:
Article
Development of a Clinical MALDI-ToF Mass Spectrometry Assay for SARS-CoV-2: Rational Design and Multi-Disciplinary Team Work.
Published in:
Diagnostics (2075-4418), 2020, v. 10, n. 10, p. 746, doi. 10.3390/diagnostics10100746
By:
- Iles, Ray K.;
- Zmuidinaite, Raminta;
- Iles, Jason K.;
- Carnell, George;
- Sampson, Alex;
- Heeney, Jonathan L.
Publication type:
Article
A naturally protective epitope of limited variability as an influenza vaccine target.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06228-8
By:
- Thompson, Craig P.;
- Lourenço, José;
- Walters, Adam A.;
- Obolski, Uri;
- Edmans, Matthew;
- Palmer, Duncan S.;
- Kooblall, Kreepa;
- Carnell, George W.;
- O’Connor, Daniel;
- Bowden, Thomas A.;
- Pybus, Oliver G.;
- Pollard, Andrew J.;
- Temperton, Nigel J.;
- Lambe, Teresa;
- Gilbert, Sarah C.;
- Gupta, Sunetra
Publication type:
Article
Inhibition of the Lectin Pathway of Complement Activation Reduces Acute Respiratory Distress Syndrome Severity in a Mouse Model of SARS-CoV-2 Infection.
Published in:
Journal of Infectious Diseases, 2024, v. 229, n. 3, p. 680, doi. 10.1093/infdis/jiad462
By:
- Ali, Youssif M;
- Carnell, George W;
- Fumagalli, Stefano;
- Mercurio, Domenico;
- Seminara, Serena;
- Lynch, Nicholas J;
- Khatri, Priyanka;
- Arachchilage, Chanuka H;
- Mascheroni, Luca;
- Kaminski, Clemens;
- George, Charlotte L;
- Stewart, Hazel;
- Yabuki, Munehisa;
- Demopulos, Gregory;
- Heeney, Jonathan L;
- Schwaeble, Wilhelm
Publication type:
Article
Pseudotype-based neutralization assays for influenza: a systematic analysis.
Published in:
Frontiers in Immunology, 2015, v. 6, p. 1, doi. 10.3389/fimmu.2015.00161
By:
- Carnell, George William;
- Ferrara, Francesca;
- Grehan, Keith;
- Thompson, Craig Peter;
- Temperton, Nigel James
Publication type:
Article

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