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- Title
Mapping the Prevalence of COVID-19 Vaccine Acceptance at the Global and Regional Level: A Systematic Review and Meta-Analysis.
- Authors
Renzi, Erika; Baccolini, Valentina; Migliara, Giuseppe; Bellotta, Ciro; Ceparano, Mariateresa; Donia, Pierluigi; Marzuillo, Carolina; De Vito, Corrado; Villari, Paolo; Massimi, Azzurra
- Abstract
Despite the availability of effective and safe vaccines, the acceptance of COVID-19 vaccination is suboptimal. In this meta-analysis we quantified the prevalence estimates of COVID-19 vaccine acceptance with a specific focus on worldwide geographical differences. We searched PubMed, Scopus, Web of Science and PsycInfo up to April 2021 (PROSPERO ID: CRD42021235328). Generalized random-effects linear models with a logit link were used to calculate the pooled estimated rate of vaccine acceptance at both the global and regional level. A meta-regression analysis was performed to assess the association between COVID-19 vaccine acceptance and various characteristics of the studies. Overall, 71 articles yielding 128 prevalence estimates were included. The pooled prevalence of COVID-19 vaccination acceptance rate was 66% (95% CI: 61–71%). This varied by geographic area, ranging from 36% (95% CI: 18–60%) in Africa to 83% (95% CI: 82–84%) in Oceania, and there was high variability between countries (15.4% Cameroon–100% Bhutan). Meta-regression analysis showed that studies that investigated COVID-19 vaccination intentions using multiple choice/scoring gave a vaccine acceptance prevalence lower than studies with only two possible answers (yes/no) (ß: −1.02 95% CI: −1.41 to −0.63). Despite some variation in the estimates, the results showed that one in three people may refuse/delay COVID-19 vaccination.
- Subjects
BHUTAN; OCEANIA; COVID-19 vaccines; VACCINE effectiveness; VACCINE hesitancy
- Publication
Vaccines, 2022, Vol 10, Issue 9, p1488
- ISSN
2076-393X
- Publication type
Article
- DOI
10.3390/vaccines10091488