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A single-cell transcriptomic map of the murine and human multiple myeloma immune microenvironment across disease stages.
- Published in:
- Journal of Hematology & Oncology, 2024, v. 17, n. 1, p. 1, doi. 10.1186/s13045-024-01629-3
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- Publication type:
- Article
Targeting S100A9 protein affects mTOR-ER stress signaling and increases venetoclax sensitivity in Acute Myeloid Leukemia.
- Published in:
- Blood Cancer Journal, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41408-023-00962-z
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- Publication type:
- Article
Myeloid-derived suppressor cells as therapeutic target in hematological malignancies.
- Published in:
- Frontiers in Oncology, 2014, v. 4, p. 1, doi. 10.3389/fonc.2014.00349
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- Publication type:
- Article
Metformin confers sensitisation to syrosingopine in multiple myeloma cells by metabolic blockage and inhibition of protein synthesis.
- Published in:
- Journal of Pathology, 2023, v. 260, n. 2, p. 112, doi. 10.1002/path.6066
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- Publication type:
- Article
Targeting the β<sub>2</sub>‐adrenergic receptor increases chemosensitivity in multiple myeloma by induction of apoptosis and modulating cancer cell metabolism.
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- Journal of Pathology, 2023, v. 259, n. 1, p. 69, doi. 10.1002/path.6020
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- Publication type:
- Article
Tumour-associated macrophage-mediated survival of myeloma cells through STAT3 activation.
- Published in:
- Journal of Pathology, 2017, v. 241, n. 4, p. 534, doi. 10.1002/path.4860
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- Publication type:
- Article
Dendritic Cell-Based Immunotherapy in Multiple Myeloma: Challenges, Opportunities, and Future Directions.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 2, p. 904, doi. 10.3390/ijms23020904
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- Publication type:
- Article
Effect of the HDAC inhibitor vorinostat on the osteogenic differentiation of mesenchymal stem cells in vitro and bone formation in vivo.
- Published in:
- Acta Pharmacologica Sinica, 2013, v. 34, n. 5, p. 699, doi. 10.1038/aps.2012.182
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- Publication type:
- Article
The prognostic value and therapeutic targeting of myeloid-derived suppressor cells in hematological cancers.
- Published in:
- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1016059
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- Publication type:
- Article
Inhibiting Histone and DNA Methylation Improves Cancer Vaccination in an Experimental Model of Melanoma.
- Published in:
- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.799636
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- Publication type:
- Article
Bisphosphonates - Mechanisms of Action in Multiple Myeloma.
- Published in:
- Acta Oncologica, 2000, v. 39, n. 7, p. 829, doi. 10.1080/028418600750063587
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- Publication type:
- Article
Homing of the Myeloma Cell Clone.
- Published in:
- Acta Oncologica, 2000, v. 39, n. 7, p. 771, doi. 10.1080/028418600750063488
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- Publication type:
- Article
Erratum: Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo.
- Published in:
- 2012
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- Publication type:
- Erratum
Erratum: Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo.
- Published in:
- 2012
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- Publication type:
- Erratum
Inhibiting Activin-A Signaling Stimulates Bone Formation and Prevents Cancer-Induced Bone Destruction In Vivo.
- Published in:
- Journal of Bone & Mineral Research, 2010, v. 25, n. 12, p. 2357, doi. 10.1002/jbmr.142
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- Publication type:
- Article
Inhibiting Dickkopf-1 (Dkk1) Removes Suppression of Bone Formation and Prevents the Development of Osteolytic Bone Disease in Multiple Myeloma.
- Published in:
- Journal of Bone & Mineral Research, 2009, v. 24, n. 3, p. 425, doi. 10.1359/jbmr.081104
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- Publication type:
- Article
Zoledronic Acid Treatment of 5T2MM-Bearing Mice Inhibits the Development of Myeloma Bone Disease: Evidence for Decreased Osteolysis, Tumor Burden and Angiogenesis, and Increased Survival.
- Published in:
- Journal of Bone & Mineral Research, 2003, v. 18, n. 3, p. 482, doi. 10.1359/jbmr.2003.18.3.482
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- Publication type:
- Article
Bone Marrow-Derived Mesenchymal Stromal Cells are Attracted by Multiple Myeloma Cell-Produced Chemokine CCL25 and Favor Myeloma Cell Growth in Vitro and In Vivo.
- Published in:
- Stem Cells, 2012, v. 30, n. 2, p. 266, doi. 10.1002/stem.787
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- Publication type:
- Article
Stimulation of invariant natural killer T cells by α-Galactosylceramide activates the JAK- STAT pathway in endothelial cells and reduces angiogenesis in the 5T33 multiple myeloma model.
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- British Journal of Haematology, 2014, v. 167, n. 5, p. 651, doi. 10.1111/bjh.13092
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- Publication type:
- Article
Thymosin β4 in multiple myeloma: friend or foe.
- Published in:
- Annals of the New York Academy of Sciences, 2010, v. 1194, n. 1, p. 125, doi. 10.1111/j.1749-6632.2010.05470.x
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- Publication type:
- Article
Mechanisms involved in the differential bone marrow homing of CD45 subsets in 5T murine models of myeloma.
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- Clinical & Experimental Metastasis, 2002, v. 19, n. 7, p. 583, doi. 10.1023/A:1020987830132
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- Publication type:
- Article
Monocyte chemoattractant protein-1 (MCP-1), secreted by bone marrow endothelial cells, induces chemoattraction of 5T multiple myeloma cells.
- Published in:
- Clinical & Experimental Metastasis, 2002, v. 19, n. 1, p. 87, doi. 10.1023/A:1013891205989
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- Publication type:
- Article
ER stress arm XBP1s plays a pivotal role in proteasome inhibition-induced bone formation.
- Published in:
- Stem Cell Research & Therapy, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13287-020-02037-3
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- Publication type:
- Article
Upregulation of miR-135b Is Involved in the Impaired Osteogenic Differentiation of Mesenchymal Stem Cells Derived from Multiple Myeloma Patients.
- Published in:
- PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0079752
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- Publication type:
- Article
Preclinical Evaluation of Invariant Natural Killer T Cells in the 5T33 Multiple Myeloma Model
- Published in:
- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0065075
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- Publication type:
- Article
Mithramycin Exerts an Anti-Myeloma Effect and Displays Anti-Angiogenic Effects through Up-Regulation of Anti-Angiogenic Factors
- Published in:
- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0062818
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- Publication type:
- Article
Polycomb Target Genes Are Silenced in Multiple Myeloma.
- Published in:
- PLoS ONE, 2010, v. 5, n. 7, p. 1, doi. 10.1371/journal.pone.0011483
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- Publication type:
- Article
The F-Actin Content of Multiple Myeloma Cells as a Measure of Their Migration.
- Published in:
- Annals of the New York Academy of Sciences, 2002, v. 973, n. 1, p. 124, doi. 10.1111/j.1749-6632.2002.tb04620.x
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- Publication type:
- Article
The Transfer of Sphingomyelinase Contributes to Drug Resistance in Multiple Myeloma.
- Published in:
- Cancers, 2019, v. 11, n. 12, p. 1823, doi. 10.3390/cancers11121823
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- Publication type:
- Article
AXL Receptor Tyrosine Kinase as a Therapeutic Target in Hematological Malignancies: Focus on Multiple Myeloma.
- Published in:
- Cancers, 2019, v. 11, n. 11, p. 1727, doi. 10.3390/cancers11111727
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- Publication type:
- Article
Cancer Associated Fibroblasts and Tumor Growth: Focus on Multiple Myeloma.
- Published in:
- Cancers, 2014, v. 6, n. 3, p. 1363, doi. 10.3390/cancers6031363
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- Publication type:
- Article
Epigenetic Modulating Agents as a New Therapeutic Approach in Multiple Myeloma.
- Published in:
- Cancers, 2013, v. 5, n. 2, p. 430, doi. 10.3390/cancers5020430
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- Publication type:
- Article
Myeloma Microenvironment.
- Published in:
- Clinical Lymphoma & Myeloma, 2009, v. 9, p. S25
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- Publication type:
- Article
Screening of amide analogues of Trichostatin A in cultures of primary rat hepatocytes: search for potent and safe HDAC inhibitors.
- Published in:
- Investigational New Drugs, 2009, v. 27, n. 4, p. 338, doi. 10.1007/s10637-008-9180-x
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- Publication type:
- Article
Multiple myeloma biology: lessons from the 5TMM models.
- Published in:
- Immunological Reviews, 2003, v. 194, n. 1, p. 196, doi. 10.1034/j.1600-065X.2003.00035.x
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- Publication type:
- Article
RNA-sequencing based first choice of treatment and determination of risk in multiple myeloma.
- Published in:
- Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1286700
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- Publication type:
- Article
The Use of Murine Models for Studying Mechanistic Insights of Genomic Instability in Multiple Myeloma.
- Published in:
- Frontiers in Genetics, 2019, p. 1, doi. 10.3389/fgene.2019.00740
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- Publication type:
- Article
The Effects of Forodesine in Murine and Human Multiple Myeloma Cells.
- Published in:
- Advances in Hematology, 2010, v. 2010, p. 1, doi. 10.1155/2010/131895
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- Publication type:
- Article
Multiple myeloma – an update on diagnosis and treatment.
- Published in:
- European Journal of Haematology, 2008, v. 81, n. 5, p. 329, doi. 10.1111/j.1600-0609.2008.01127.x
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- Publication type:
- Article
Histone deacetylase inhibition and the regulation of cell growth with particular reference to liver pathobiology.
- Published in:
- Journal of Cellular & Molecular Medicine, 2009, v. 13, n. 9b, p. 2990, doi. 10.1111/j.1582-4934.2009.00831.x
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- Publication type:
- Article
Bisphosphonates and osteoprotegerin as inhibitors of myeloma bone disease.
- Published in:
- Cancer (0008543X), 2003, v. 97, n. S3, p. 818, doi. 10.1002/cncr.11125
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- Publication type:
- Article
Targeting mTOR signaling pathways in multiple myeloma: biology and implication for therapy.
- Published in:
- Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-024-01699-3
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- Publication type:
- Article
Complement C3a activates osteoclasts by regulating the PI3K/PDK1/SGK3 pathway in patients with multiple myeloma.
- Published in:
- Cancer Biology & Medicine, 2021, v. 18, n. 3, p. 721, doi. 10.20892/j.issn.2095-3941.2020.0430
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- Publication type:
- Article
Epigenetic Modifiers: Anti-Neoplastic Drugs With Immunomodulating Potential.
- Published in:
- Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.652160
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- Publication type:
- Article
Targeting the IGF-1R using picropodophyllin in the therapeutical 5T2MM mouse model of multiple myeloma: Beneficial effects on tumor growth, angiogenesis, bone disease and survival.
- Published in:
- International Journal of Cancer, 2007, v. 121, n. 8, p. 1857, doi. 10.1002/ijc.22845
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- Publication type:
- Article
Apomine™, an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and is associated with a modulation of myeloma in vivo.
- Published in:
- International Journal of Cancer, 2007, v. 120, n. 8, p. 1657, doi. 10.1002/ijc.22478
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- Publication type:
- Article
Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche.
- Published in:
- Nature Communications, 2015, v. 6, n. 12, p. 8983, doi. 10.1038/ncomms9983
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- Publication type:
- Article
The anaphase-promoting complex/cyclosome: a new promising target in diffuse large B-cell lymphoma and mantle cell lymphoma.
- Published in:
- 2019
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- Publication type:
- journal article
DNMTi/HDACi combined epigenetic targeted treatment induces reprogramming of myeloma cells in the direction of normal plasma cells.
- Published in:
- 2018
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- Publication type:
- journal article
Maternal embryonic leucine zipper kinase is a novel target for diffuse large B cell lymphoma and mantle cell lymphoma.
- Published in:
- Blood Cancer Journal, 2019, v. 9, n. 12, p. 1, doi. 10.1038/s41408-019-0249-x
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- Publication type:
- Article