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- Title
Relationship of SARS-CoV-2 Antigen and Reverse Transcription PCR Positivity for Viral Cultures.
- Authors
Currie, Dustin W.; Shah, Melisa M.; Salvatore, Phillip P.; Ford, Laura; Whaley, Melissa J.; Meece, Jennifer; Ivacic, Lynn; Thornburg, Natalie J.; Tamin, Azaibi; Harcourt, Jennifer L.; Folster, Jennifer; Medrzycki, Magdalena; Jain, Shilpi; Wong, Phili; ard, Kimberly Goff; Gieryn, Douglas; Kahrs, Juliana; Langolf, Kimberly; Zochert, Tara; Hsu, Christopher H.
- Abstract
We assessed the relationship between antigen and reverse transcription PCR (RT-PCR) test positivity and successful virus isolation. We found that antigen test results were more predictive of virus recovery than RT-PCR results. However, virus was isolated from some antigen-negative and RT-PCR‒positive paired specimens, providing support for the Centers for Disease Control and Prevention antigen testing algorithm.
- Subjects
CENTERS for Disease Control &; Prevention (U.S.); VIRUS isolation; ANTIGENS; SARS-CoV-2; TRANSGENIC organisms; REVERSE transcriptase polymerase chain reaction
- Publication
Emerging Infectious Diseases, 2022, Vol 28, Issue 3, p717
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/eid2803.211747