We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Genotyping Approach for Potential Common Source of Enterocytozoon bieneusi Infection in Hematology Unit.
- Authors
Desoubeaux, Guillaume; Nourrisson, Céline; Moniot, Maxime; De Kyvon, Marie-Alix; Bonnin, Virginie; De La Bretonniére, Marjan Ertault; Morange, Virginie; Bailly, Éric; Lemaignen, Adrien; Morio, Florent; Poirier, Philippe
- Abstract
Microsporidiosis is a fungal infection that generally causes digestive disorders, especially in immunocompromised hosts. Over a 4-day period in January 2018, 3 patients with hematologic malignancies who were admitted to the hematology unit of a hospital in France received diagnoses of Enterocytozoon bieneusi microsporidiosis. This unusually high incidence was investigated by sequence analysis at the internal transcribed spacer rDNA locus and then by 3 microsatellites and 1 minisatellite for multilocus genotyping. The 3 isolates had many sequence similarities and belonged to a new genotype closely related to genotype C. In addition, multilocus genotyping showed high genetic distances with all the other strains collected from epidemiologically unrelated persons; none of these strains belonged to the new genotype. These data confirm the epidemiologic link among the 3 patients and support a common source of infection.
- Subjects
FRANCE; HEMATOLOGY; HEMATOLOGIC malignancies; MYCOSES; MICROSPORIDIOSIS; IMMUNOCOMPROMISED patients; BEGOMOVIRUSES
- Publication
Emerging Infectious Diseases, 2019, Vol 25, Issue 9, p1625
- ISSN
1080-6040
- Publication type
journal article
- DOI
10.3201/eid2509.190311