We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Bloodstream Infections among HIV-Infected Outpatients, Southeast Asia.
- Authors
Varma, Jay K.; McCarthy, Kimberly D.; Tasaneeyapan, Theerawit; Monkongdee, Patama; Kimerling, Michael E.; Buntheoun, Eng; Sculler, Delphine; Keo, Chantary; Phanuphak, Praphan; Teeratakulpisarn, Nipat; Udomsantisuk, Nibondh; Dung, Nguyen H.; Lan, Nguyen T. N.; Yen, Nguyen T. B.; Cain, Kevin P.
- Abstract
Bloodstream infections (BSIs) are a major cause of illness in HIV-infected persons. To evaluate prevalence of and risk factors for BSIs in 2,009 HIV-infected outpatients in Cambodia, Thailand, and Vietnam, we performed a single Myco/F Lytic blood culture. Fifty-eight (2.9%) had a clinically significant BSI (i.e., a blood culture positive for an organism known to be a pathogen). Mycobacterium tuberculosis accounted for 31 (54%) of all BSIs, followed by fungi (13 [22%]) and bacteria (9 [16%]). Of patients for whom data were recorded about antiretroviral therapy, 0 of 119 who had received antiretroviral therapy for ≥14 days had a BSI, compared with 3% of 1,801 patients who had not. In multivariate analysis, factors consistently associated with BSI were fever, low CD4+ T-lymphocyte count, abnormalities on chest radiograph, and signs or symptoms of abdominal illness. For HIV-infected outpatients with these risk factors, clinicians should place their highest priority on diagnosing tuberculosis.
- Subjects
CAMBODIA; THAILAND; VIETNAM; HIV-positive persons; DISEASE prevalence; PATHOGENIC microorganisms; MYCOBACTERIUM tuberculosis; HIGHLY active antiretroviral therapy; DISEASES
- Publication
Emerging Infectious Diseases, 2010, Vol 16, Issue 10, p1569
- ISSN
1080-6040
- Publication type
Article
- DOI
10.3201/eid1610.091686