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Structure- and ligand-based drug design approaches for neglected tropical diseases.
Published in:
Pure & Applied Chemistry, 2012, v. 84, n. 9, p. 1857, doi. 10.1351/PAC-CON-11-11-07
By:
- Guido, Rafael V. C.;
- Oliva, Glaucius;
- Andricopulo, Adriano D.
Publication type:
Article
Editorial: Antimalarial chemotherapy in the XXIst century.
Published in:
Frontiers in Pharmacology, 2023, v. 13, p. 1, doi. 10.3389/fphar.2022.1118683
By:
- Gomes, Paula;
- Guido, Rafael V. C.
Publication type:
Article
Synthesis, Structure–Activity Relationships, and Parasitological Profiling of Brussonol Derivatives as New Plasmodium falciparum Inhibitors.
Published in:
Pharmaceuticals (14248247), 2022, v. 15, n. 7, p. N.PAG, doi. 10.3390/ph15070814
By:
- Barbosa, Camila S.;
- Ahmad, Anees;
- Maluf, Sarah El Chamy;
- Moura, Igor M. R.;
- Souza, Guilherme E.;
- Guerra, Giovanna A. H.;
- Barros, Roberto R. Moraes;
- Gazarini, Marcos L.;
- Aguiar, Anna C. C.;
- Burtoloso, Antonio C. B.;
- Guido, Rafael V. C.
Publication type:
Article
Pattern Recognition Techniques Applied to the Study of Leishmanial Glyceraldehyde-3-Phosphate Dehydrogenase Inhibition.
Published in:
International Journal of Molecular Sciences, 2014, v. 15, n. 2, p. 3186, doi. 10.3390/ijms15023186
By:
- Lozano, Norka B. H.;
- Oliveira, Rafael F.;
- Weber, Karen C.;
- Honorio, Kathia M.;
- Guido, Rafael V. C.;
- Andricopulo, Adriano D.;
- de Sousa, Alexsandro G.;
- da Silva, Albérico B. F.
Publication type:
Article
Structural requirements for the collagenase and elastase activity of cathepsin K and its selective inhibition by an exosite inhibitor.
Published in:
Biochemical Journal, 2015, v. 465, n. 1, p. 163, doi. 10.1042/BJ20140809
By:
- Sharma, Vidhu;
- Panwar, Preety;
- O'Donoghue, Anthony J.;
- Cui, Haoran;
- Guido, Rafael V. C.;
- Cralk, Charles S.;
- Bromme, Dieter
Publication type:
Article
Friedelin Synthase from Maytenus ilicifolia: Leucine 482 Plays an Essential Role in the Production of the Most Rearranged Pentacyclic Triterpene.
Published in:
Scientific Reports, 2016, p. 36858, doi. 10.1038/srep36858
By:
- Souza-Moreira, Tatiana M.;
- Alves, Thaís B.;
- Pinheiro, Karina A.;
- Felippe, Lidiane G.;
- De Lima, Gustavo M. A.;
- Watanabe, Tatiana F.;
- Barbosa, Cristina C.;
- Santos, Vânia A. F. F. M.;
- Lopes, Norberto P.;
- Valentini, Sandro R.;
- Guido, Rafael V. C.;
- Furlan, Maysa;
- Zanelli, Cleslei F.
Publication type:
Article
Biliverdin targets enolase and eukaryotic initiation factor 2 (eIF2α) to reduce the growth of intraerythrocytic development of the malaria parasite Plasmodium falciparum.
Published in:
Scientific Reports, 2016, p. 22093, doi. 10.1038/srep22093
By:
- Alves, Eduardo;
- Maluf, Fernando V.;
- Bueno, Vânia B.;
- Guido, Rafael V. C.;
- Oliva, Glaucius;
- Singh, Maneesh;
- Scarpelli, Pedro;
- Costa, Fahyme;
- Sartorello, Robson;
- Catalani, Luiz H.;
- Brady, Declan;
- Tewari, Rita;
- Garcia, Celia R. S.
Publication type:
Article
The Methionine 549 and Leucine 552 Residues of Friedelin Synthase from Maytenus ilicifolia Are Important for Substrate Binding Specificity.
Published in:
Molecules, 2021, v. 26, n. 22, p. 6806, doi. 10.3390/molecules26226806
By:
- Mazzeu, Bruna F.;
- Souza-Moreira, Tatiana M.;
- Oliveira, Andrew A.;
- Remlinger, Melissa;
- Felippe, Lidiane G.;
- Valentini, Sandro R.;
- Guido, Rafael V. C.;
- Zanelli, Cleslei F.;
- Furlan, Maysa
Publication type:
Article
Molecular Cloning and Biochemical Characterization of Iron Superoxide Dismutase from Leishmania braziliensis.
Published in:
Molecular Biotechnology, 2018, v. 60, n. 8, p. 595, doi. 10.1007/s12033-018-0095-2
By:
- Brito, Camila C. B.;
- Maluf, Fernando V.;
- de Lima, Gustavo M. A.;
- Guido, Rafael V. C.;
- Castilho, Marcelo S.
Publication type:
Article
Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase.
Published in:
Nature Communications, 2017, v. 8, n. 3, p. 14764, doi. 10.1038/ncomms14764
By:
- Godoy, Andre S.;
- Lima, Gustavo M. A.;
- Oliveira, Ketllyn I. Z.;
- Torres, Naiara U.;
- Maluf, Fernando V.;
- Guido, Rafael V. C.;
- Oliva, Glaucius
Publication type:
Article
QSAR studies on benzothiophene derivatives as Plasmodium falciparum N‐myristoyltransferase inhibitors: Molecular insights into affinity and selectivity.
Published in:
Drug Development Research, 2022, v. 83, n. 2, p. 264, doi. 10.1002/ddr.21646
By:
- Garcia, Mariana L.;
- de Oliveira, Andrew A.;
- Bueno, Renata V.;
- Nogueira, Victor H. R.;
- de Souza, Guilherme E.;
- Guido, Rafael V. C.
Publication type:
Article
Editorial: Antimalarial chemotherapy in the XXIst century, volume II.
Published in:
Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1229764
By:
- Gomes, Paula;
- Guido, Rafael V. C.
Publication type:
Article
Non-Toxic Dimeric Peptides Derived from the Bothropstoxin-I Are Potent SARS-CoV-2 and Papain-like Protease Inhibitors.
Published in:
Molecules, 2021, v. 26, n. 16, p. 4896, doi. 10.3390/molecules26164896
By:
- Freire, Marjorie C. L. C.;
- Noske, Gabriela D.;
- Bitencourt, Natália V.;
- Sanches, Paulo R. S.;
- Santos-Filho, Norival A.;
- Gawriljuk, Victor O.;
- de Souza, Eduardo P.;
- Nogueira, Victor H. R.;
- de Godoy, Mariana O.;
- Nakamura, Aline M.;
- Fernandes, Rafaela S.;
- Godoy, Andre S.;
- Juliano, Maria A.;
- Peres, Bianca M.;
- Barbosa, Cecília G.;
- Moraes, Carolina B.;
- Freitas-Junior, Lucio H. G.;
- Cilli, Eduardo M.;
- Guido, Rafael V. C.;
- Oliva, Glaucius
Publication type:
Article
Identification of Electronic and Structural Descriptors of Adenosine Analogues Related to Inhibition of Leishmanial Glyceraldehyde-3-Phosphate Dehydrogenase.
Published in:
Molecules, 2013, v. 18, n. 5, p. 5032, doi. 10.3390/molecules18055032
By:
- Lozano, Norka B. H.;
- Oliveira, Rafael F.;
- Weber, Karen C.;
- Honorio, Kathia M.;
- Guido, Rafael V.;
- Andricopulo, Adriano D.;
- Da Silva, Albérico B. F.
Publication type:
Article
Optimization of Plasmodium vivax infection of colonized Amazonian Anopheles darlingi.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-44556-y
By:
- Andrade, Alice O.;
- Santos, Najara Akira C.;
- Bastos, Alessandra S.;
- Pontual, José Daniel C.;
- Araújo, Cristiane S.;
- Lima, Analice S.;
- Martinez, Leandro N.;
- Ferreira, Amália S.;
- Aguiar, Anna Caroline C.;
- Teles, Carolina B. G.;
- Guido, Rafael V. C.;
- Santana, Rosa A.;
- Lopes, Stefanie C. P.;
- Medeiros, Jansen F.;
- Rizopoulos, Zaira;
- Vinetz, Joseph M.;
- Campo, Brice;
- Lacerda, Marcus Vinicius G.;
- Araújo, Maisa S.
Publication type:
Article
A composite docking approach for the identification and characterization of ectosteric inhibitors of cathepsin K.
Published in:
PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0186869
By:
- Law, Simon;
- Panwar, Preety;
- Li, Jody;
- Aguda, Adeleke H.;
- Jamroz, Andrew;
- Guido, Rafael V. C.;
- Brömme, Dieter
Publication type:
Article
The (5 Z)-5-Pentacosenoic and 5-Pentacosynoic Acids Inhibit the HIV-1 Reverse Transcriptase.
Published in:
Lipids, 2015, v. 50, n. 10, p. 1043, doi. 10.1007/s11745-015-4064-2
By:
- Moreira, Lizabeth Giménez;
- Orellano, Elsie A.;
- Rosado, Karolyna;
- Guido, Rafael V. C.;
- Andricopulo, Adriano D.;
- Soto, Gabriela Ortiz;
- Rodríguez, José W.;
- Sanabria‐Ríos, David J.;
- Carballeira, Néstor M.
Publication type:
Article

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