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- Title
Optimal Definitions for Abdominal Obesity and the Metabolic Syndrome in Andean Hispanics: The PREVENCION Study.
- Authors
Medina-Lezama, Josefina; Pastorius, Catherine A.; Zea-Diaz, Humberto; Bernabe-Ortiz, Antonio; Corrales-Medina, Fernando; Morey-Vargas, Oscar Leopoldo; Chirinos, Diana Andrea; Muñoz-Atahualpa, Edgar; Chirinos-Pacheco, Julio; Chirinos, Julio Alonso
- Abstract
OBJECTIVE- We aimed to establish optimal definitions for abdominal obesity and metabolic syndrome (MetS) among Andean adults. RESEARCH DESIGN AND METHODS-- Among 1,448 Andean adults, we assessed the relationship between waist circumference and subclinical vascular disease assessed by carotid intima-media thickness (cIMT) and manifest cardiovascular disease (M-CVD). RESULTS -- Optimal waist circumference cutoffs to classify individuals with abnormal cIMT or M-CVD were >97 and >87 cm in men and women, respectively. With these cutoffs, there was substantial disagreement between the original American Heart Association/National Heart, Lung and Blood Institute (AHA/NHLBI) and the recently updated MetS definition, particularly among men (κ = 0.85). Subjects with MetS identified by the updated definition but not meeting the original AHA/NHLBI MetS criteria demonstrated significantly increased cIMT (P < 0.001) compared with subjects who did not meet the MetS criteria by either definition. CONCLUSIONS-- Our findings support the use of ethnic-specific waist circumference cutoffs and the updated MetS definition in Andean adults.
- Subjects
OBESITY; METABOLIC syndrome; PERIPHERAL vascular diseases; VASCULAR diseases; DIABETES complications; DIABETES
- Publication
Diabetes Care, 2010, Vol 33, Issue 6, p1385
- ISSN
0149-5992
- Publication type
Article
- DOI
10.2337/dc09-2353