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- Title
European Biological Variation Study (EuBIVAS): within- and between-subject biological variation estimates for serum thyroid biomarkers based on weekly samplings from 91 healthy participants.
- Authors
Bottani, Michela; Aarsand, Aasne K.; Banfi, Giuseppe; Locatelli, Massimo; Coşkun, Abdurrahman; Díaz-Garzón, Jorge; Fernandez-Calle, Pilar; Sandberg, Sverre; Ceriotti, Ferruccio; Carobene, Anna
- Abstract
The NHSP calculated for TG based on the EuBIVAS data is five samples with a 10% approximation and three with 15% approximation. The EuBIVAS CV SB I I i sb estimate for TG (all subjects: 10.3% (95% CI; 9.8-10.9)) is lower than the estimates recently reported by Mairesse et al. (15.4%, 95% CI; 13.3-18.3) [[33]] and by Feldt-Rasmussen, even if for the latter, 12.8%, is not significantly different based on evaluation of the 95% CI; 10.0-17.1 [[35]]. Keywords: analytical performance specification; biological variation; reference change value; thyroid EN analytical performance specification biological variation reference change value thyroid 523 532 10 03/11/22 20220301 NES 220301 Introduction Thyroid pathologies represent the most common endocrine disorders after diabetes.
- Subjects
BIOLOGICAL variation; THYROID gland; THYROID hormone regulation; THYROTROPIN; PROSTATE-specific antigen; THYROID gland function tests
- Publication
Clinical Chemistry & Laboratory Medicine, 2022, Vol 60, Issue 4, p523
- ISSN
1434-6621
- Publication type
Article
- DOI
10.1515/cclm-2020-1885