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- Title
Anti-angiogenic effects of biotechnological therapies in rheumatic diseases.
- Authors
Cantatore, Francesco Paolo; Maruotti, Nicola; Corrado, Addolorata; Ribatti, Domenico
- Abstract
Introduction: Angiogenesis plays a key role in the pathogenesis of numerous rheumatic diseases, such as rheumatoid arthritis, psoriatic arthritis and vasculitides. Therefore, the inhibition of pathological angiogenesis may be considered a useful therapeutical approach in these rheumatic diseases. Methods: This review article is based on a literature research about the role of biotechnological therapies in angiogenesis inhibition. Results and conclusions: Several evidences have demonstrated a role for biotechnological therapies in angiogenesis inhibition. Nevertheless, further research and clinical trials are needed to better quantify the real impact of biotechnological therapies on pathological angiogenesis.
- Subjects
BIOTECHNOLOGICAL microorganisms; RHEUMATOID arthritis; VASCULITIS; PSORIATIC arthritis; CLINICAL trials
- Publication
Biologics: Targets & Therapy, 2017, Vol 11, p123
- ISSN
1177-5475
- Publication type
Article
- DOI
10.2147/BTT.S143674