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- Title
Haematological Effects of Oral Cobalamin Preparations on Patients with Megaloblastic Anaemia.
- Authors
Kondo, Haruki
- Abstract
We investigated the haematological effects of a massive dose of oral cobalamin (vitamin B[sub 12] ) on patients with cobalamin deficiency anaemia who had severe anaemia with a few neurological impairments and found that oral treatment was almost as effective as conventional injection therapy. The recovery of haematological indices with oral cobalamin preparations was slightly slower than with parenteral preparations, although the subjective symptoms disappeared soon after the start of therapy. The results of this study indicate that oral treatment keeps the cobalamin body stores satisfactorily filled and might be useful for older patients in whom injecting might be difficult.
- Subjects
VITAMIN B12 deficiency; ANEMIA; VITAMIN B12; MEGALOBLASTIC anemia; PERNICIOUS anemia; GASTRECTOMY complications
- Publication
Acta Haematologica, 1998, Vol 99, Issue 4, p200
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000040839