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- Title
Shared trans‐ancestry genetic etiology between panic disorder and anxiety disorders.
- Authors
Ohi, Kazutaka; Otowa, Takeshi; Shimada, Mihoko; Sugiyama, Shunsuke; Tanahashi, Shunsuke; Kaiya, Hisanobu; Nishimura, Fumichika; Sasaki, Tsukasa; Tanii, Hisashi; Shioiri, Toshiki
- Abstract
GLO:82I/01jun21:pcn13214-fig-0001.jpg PHOTO (COLOR): 1 Effects of polygenic risk scores for European anxiety disorders (Anxiety NeuroGenetics Study [ANGST], iPSYCH, UK Biobank [UKBB], and a meta-analysis of these genome-wide association studies [META]) at each threshold (PT cutoff) on the risk of panic disorder (PD) in Japanese patients. Panic disorder (PD), an anxiety disorder, is modestly heritable. The PRS obtained from the European anxiety UKBB patients were significantly higher in Japanese patients with PD than in HC (Fig.
- Subjects
ANXIETY disorders; PANIC disorders; ETIOLOGY of diseases; GENERALIZED anxiety disorder; GENOME-wide association studies; AGORAPHOBIA; LONELINESS
- Publication
Psychiatry & Clinical Neurosciences, 2021, Vol 75, Issue 6, p209
- ISSN
1323-1316
- Publication type
Article
- DOI
10.1111/pcn.13214