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- Title
Long-Term Clinical Performance of a Central Venous Oxygen Saturation Sensor for Rate Adaptive Cardiac Pacing.
- Authors
Faerestrand, Svein; Ohm, Ole-Jorgen; Stangeland, Lodve; Heynen, Henri; Moore, Alan
- Abstract
Rate adaptive ventricular pacemakers using central venous oxygen saturation (O2Sat) to control the pacing rate have been implanted in 14 patients (mean age 71 years), with a mean follow-up period of 44 months (range 2-63 months). In eight patients the pacemakers were replaced due to signs of battery depletion after an implant duration of 39-58 months. During bicycle exercise testing the O2Sat decreased on average from 61% ± 4% at rest to 36% ± 4% (P < 0,0001) at peak exercise, and the maximum pacing rate was 122 ± 5 beats/min. the time delay until the O2Sat bad dropped 10%, 65%, and 90% of the total reduction during exercise was 4.8 ± 0.9 seconds, 39.8 ± 3.8 seconds, and 71.3 ± 7.5 seconds, respectively. the O2Sat decreased 9.4% ± 2% (P < 0.005) from resting supine to resting sitting. Oxygen breathing increased the telemetered O2Sat from the pacemaker by 8,4% ± 1% (P < 0.001). During follow-up the O2Sats were relatively stable in 50% of" the patients, but demonstrated significant fluctuations in the others. At 1-year invasive follow-up O2Sat measured by the pacemaker decreased 22% ± 2%, and in blood samples from the right ventricle 22% ± 2% from rest to 3 minutes exercise at 25 watts. there was a significant correlation between O2Sat measured by the pacemaker and in blood samples from right ventricle (n = 105; r = 0.73; P < 0.001). In two patients the O2Sat dropped significantly during pneumonia. In another patient episodes of angina pectoris was associated with low O2Sat and a concomitant fast pacing rate.
- Subjects
CENTRAL venous pressure; OXYGEN in the body; CARDIAC pacing; ARRHYTHMIA treatment; ELECTRIC stimulation; DETECTORS
- Publication
Pacing & Clinical Electrophysiology, 1994, Vol 17, Issue 8, p1355
- ISSN
0147-8389
- Publication type
Article
- DOI
10.1111/j.1540-8159.1994.tb02455.x