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- Title
Radiation therapy for vulvar cancer: consensus technical guidelines of the GINECOR working group of the Spanish Society of Radiation Oncology. Part 2: radiotherapy recommendations.
- Authors
Cordoba Largo, Sofia; Rodriguez Rodriguez, Isabel; Rodriguez Villalba, Silvia; Najjari Jamal, Dina; Anchuelo Latorre, Javier; Celada Alvarez, Francisco; Garcia Cabezas, Sonia; de la Fuente Alonso, Cristina; Couselo Paniagua, Luz; Martinez Montesinos, Irene; Villafranca Iturre, Elena; Belinchon Olmeda, Belen; Farga Albiol, Dolores; Navarrete Solano, Paola Andrea; Sanchez Belda, Maria
- Abstract
Purpose: The present consensus statement was developed by the GINECOR working group on behalf of the Spanish Society of Radiation Oncology (SEOR). This document provides an up-to-date review of the technical aspects in radiation treatment of vulvar cancer. Methods: A two-round modified Delphi study was conducted to reach consensus on the appropriateness of technical aspects of external beam radiotherapy and brachytherapy. Three clinical scenarios were proposed: adjuvant treatment of vulvar cancer, radiation treatment of locally advanced vulvar carcinoma and locoregional recurrences. After the first round, an extensive analysis of current medical literature from peer-reviewed journal was performed to define evidence-based treatment options. In the second round, participants were asked to indicate their level of agreement with the preliminary recommendations according to the GRADE (Grade of Recommendation, Assessment, Development, and Evaluation) criteria, as follows: strongly agree; agree; neither agree nor disagree; disagree and strongly disagree. Results: The main recommendations on external beam radiotherapy and brachytherapy, both in adjuvant setting and local advanced disease are summarized. Recommendations include treatment technique, treatment volume, and doses in target and organs at-risk. Taking into consideration the different clinical scenarios of recurrent disease, the radiation treatment should be individualized. Conclusions: In the absence of robust clinical data, these recommendations may help to select the optimal radiotherapy approach for this relatively rare cancer.
- Publication
Clinical & Translational Oncology, 2023, Vol 25, Issue 7, p2169
- ISSN
1699-048X
- Publication type
Article
- DOI
10.1007/s12094-023-03101-z