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- Title
Detection of Hepatitis C Viral RNA in Serum of a Patient with Acute Non A, Non B Hepatitis.
- Authors
Waxman, Irving; Baker, Bennie; Feinstone, Stephen M.; Di Bisceglie, Adrian M.
- Abstract
The sequence of serologic events in a patient with acute type C hepatitis associated with intravenous drug abuse is described. Hepatitis C virus (HCV) ribonucleic acid was detectable in serum during the acute episode of hepatitis, whereas antibody to the hepatitis C virus appeared later, after the acute illness had subsided. The patient developed chronic hepatitis with persistently elevated serum aminotransferase activities. Both hepatitis C viral ribonucleic acid and antibody to hepatitis C virus persisted in serum, together with elevated serum aminotransferases. Thus, detection of HCV RNA may be useful in the diagnosis of acute type C hepatitis, particularly in the absence of detectable antibody to the hepatitis C virus.
- Subjects
HEPATITIS C; INTRAVENOUS drug abuse; RNA; SERUM; IMMUNOGLOBULINS
- Publication
American Journal of Gastroenterology (Springer Nature), 1991, Vol 86, Issue 9, p1240
- ISSN
0002-9270
- Publication type
Article